Canuel René, de Grosbois Sylvie Boucher, Atikessé Laura, Lucotte Marc, Arp Paul, Ritchie Charles, Mergler Donna, Chan Hing Man, Amyot Marc, Anderson Robin
Institute of Environmental Sciences, Université du Québec à Montréal, Montréal, Québec, Canada.
Environ Health Perspect. 2006 Feb;114(2):302-6. doi: 10.1289/ehp.7857.
Epidemiologic studies commonly use mercury (Hg) level in hair as a valid proxy to estimate human exposure to methylmercury (MeHg) through fish consumption. This study presents the results yielded by a complete data set on fish consumption habits, Hg levels in edible fish resources, and corresponding Hg accumulation in hair, gathered in three distinct communities of eastern Canada. For one of these communities, the average hair Hg concentration was 14 times less than the expected value based on calculated daily oral exposure and current knowledge of MeHg metabolism. This finding could be explained by differences in specific genetic characteristics and/or interactive effects of other dietary components.
流行病学研究通常将头发中的汞（Hg）水平作为一个有效的指标，来估计人类通过食用鱼类接触甲基汞（MeHg）的情况。本研究展示了一个完整数据集的结果，该数据集收集了加拿大东部三个不同社区的鱼类消费习惯、可食用鱼类资源中的汞水平以及头发中相应的汞积累情况。对于其中一个社区，根据每日口服摄入量计算和当前对甲基汞代谢的了解，其头发汞平均浓度比预期值低14倍。这一发现可以用特定遗传特征的差异和/或其他饮食成分的交互作用来解释。
