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食管胃切除术后的分胃底折叠术

The split-stomach fundoplication after esophagogastrectomy.

作者信息

Velanovich Vic, Mohlberg Nathan

机构信息

Division of General Surgery, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA.

出版信息

J Gastrointest Surg. 2006 Feb;10(2):178-83, discussion184-5. doi: 10.1016/j.gassur.2005.10.014.

Abstract

Two complications associated with esophagogastrectomy are anastomotic leak and gastroesophageal reflux. We describe here a modification of an intrathoracic esophagogastrostomy using the gastric fundus to address these issues. After completion of the esophagogastrectomy, the fundus is divided to produce "wings." After the esophagogastrostomy is performed, the wings are used to form a wrap around the anastomosis. This wrap is secured to the esophagus and to the stomach. All patients undergoing the split-stomach fundoplication were compared with all patients undergoing standard esophagogastrectomies. End points were in-hospital mortality, anastomotic leak, and postoperative endoscopic dilation. All living patients were contacted and questioned about refluxlike symptoms and completed the Gastroesophageal Reflux Disease-Health Related Quality of Life (GERD-HRQL) symptom severity questionnaire. Twenty-six patients underwent the split-stomach fundoplication (wrap group), compared to 54 patients undergoing standard resection (no wrap group). Occurrence of end points in the wrap vs. no wrap groups were, respectively, in-hospital mortality, 3.8% vs. 7.4% (P = NS); anastomotic leak, 0% vs. 17% (P = 0.03); reflux symptoms 20% vs. 60% (P < 0.001); postoperative dilation, 40% vs. 30% (P = NS). The median total GERD-HRQL score was 5 for the wrap group vs. 14 for the no wrap group (P = 0.03). The addition of the split-stomach fundoplication to esophagogastrectomy may decrease the incidence of anastomotic leak and postoperative refluxlike symptoms.

摘要

与食管胃切除术相关的两种并发症是吻合口漏和胃食管反流。我们在此描述一种使用胃底的胸内食管胃吻合术改良方法来解决这些问题。食管胃切除术后,将胃底分开形成“翼”。完成食管胃吻合术后,用这些“翼”在吻合口周围形成一个包裹。这个包裹固定在食管和胃上。将所有接受裂胃底折叠术的患者与所有接受标准食管胃切除术的患者进行比较。观察终点为住院死亡率、吻合口漏和术后内镜扩张。联系了所有在世患者,询问他们有无反流样症状,并完成了胃食管反流病健康相关生活质量(GERD-HRQL)症状严重程度问卷。26例患者接受了裂胃底折叠术(包裹组),相比之下,54例患者接受了标准切除术(无包裹组)。包裹组与无包裹组观察终点的发生率分别为:住院死亡率,3.8%对7.4%(P=无统计学意义);吻合口漏,0%对17%(P=0.03);反流症状,20%对60%(P<0.001);术后扩张,40%对30%(P=无统计学意义)。包裹组GERD-HRQL总评分中位数为5,无包裹组为14(P=0.03)。在食管胃切除术中增加裂胃底折叠术可能会降低吻合口漏和术后反流样症状的发生率。

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