波前引导消融术：与传统消融术相比的疗效证据。
Wavefront-guided ablation: evidence for efficacy compared to traditional ablation.
作者信息
Netto Marcelo V, Dupps William, Wilson Steven E
机构信息
The Cole Eye Institute, The Cleveland Clinic Foundation, Cleveland, Ohio, USA, and Department of Ophthalmology, University of São Paulo, São Paulo, Brazil.
出版信息
Am J Ophthalmol. 2006 Feb;141(2):360-368. doi: 10.1016/j.ajo.2005.08.034.
PURPOSE
To provide an evidence-based overview of wavefront-guided refractive surgery outcomes, benefits, and limitations.
DESIGN
Literature review.
METHODS
Review of FDA study reports and indexed, peer-reviewed literature.
RESULTS
More than 400 reports investigating wavefront applications in refractive surgery exist, but studies comparing the outcomes of wavefront-guided treatment with conventional treatment are few in number. Available studies do not overwhelmingly demonstrate superior visual results attributable to a wavefront-guided approach.
CONCLUSIONS
While wavefront-guided refractive surgery provides excellent results, evidence is limited that it outperforms conventional laser in situ keratomileusis that incorporates broad ablation zones, smoothing to the periphery, eye-trackers, and other technological refinements. However, it is evident that wavefront-customized ablation holds a promising future and merits ongoing investigation.
目的
提供基于证据的波前引导屈光手术的结果、益处及局限性概述。
设计
文献综述。
方法
查阅美国食品药品监督管理局（FDA）研究报告及索引的同行评审文献。
结果
有400多篇关于波前技术在屈光手术中应用的研究报告，但比较波前引导治疗与传统治疗结果的研究数量较少。现有研究并未压倒性地证明波前引导方法能带来更优的视觉效果。
结论
虽然波前引导屈光手术效果良好，但证据有限，表明其并不优于结合了宽消融区、周边平滑、眼球跟踪器及其他技术改进的传统准分子原位角膜磨镶术。然而，波前定制消融显然前景广阔，值得持续研究。
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