Meng Guang, Li Chunlin, Cai Qiongxiang, Xie Chunmei
Department of Otorhinolaryngology, Haikou People's Hospital, Haikou, 570208, China.
Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2005 Nov;19(22):1044-5.
To discover varieties of sensitization pollens and improve specific diagnosis against tropic pollinosis by the field survey of tropic plants.
(1) All of the chosen 20 tropic plants widely located, with enormous quantity and more pollens were identified the family, genus and species by specialists. And their pollens gathered in full bloom period were delivered to the chemical reagent works of union Hospital, Beijing and manufactured, according to clinical standards, into idiotoxins. (2) Five hundred patients were chosen randomly from May, 2003 to August, 2004 among those who came to our department and were suffering from allergic rhinitis, slow urticaria, allergic taraxis, allergic asthma and deviancy asthma. They were aged 5-72, altogether 285 male and 215 female, and agreed to be observed. Experiments included skin pricking and intracutaneous test.
The 20 clinical skin prick tests of tropic plants pollens idiotoxin proved that the positive reaction rate was 5 of which was over 50%, 6 of which 40%-49%, 3 of which 30%-39%, 4 of which 20%-29%, 2 of which 10%-20%, 40%-49%.
The tropic plants survey, pollen gathering, idiotoxin manufacturing, clinic intracutaneous test and sensitization discovery have not only increased varieties of tropic sensitization pollen idiotoxins but also improved specific diagnosis of pollinosis in tropic areas.
通过对热带植物的实地调查，发现致敏花粉种类，提高对热带花粉症的特异性诊断。
（1）选取20种广泛分布、数量众多且花粉量大的热带植物，由专家鉴定其科、属、种。在其花期采集花粉，送至北京协和医院化学试剂厂，按临床标准制成自身变应原。（2）2003年5月至2004年8月，从前来我科就诊的过敏性鼻炎、慢性荨麻疹、过敏性紫癜、过敏性哮喘及变应性哮喘患者中随机选取500例。年龄5 - 72岁，男285例，女215例，均同意接受观察。实验包括皮肤点刺试验和皮内试验。
20种热带植物花粉自身变应原的临床皮肤点刺试验结果显示，阳性反应率为：5种超过50%，6种为40% - 49%，3种为30% - 39%，4种为20% - 29%，2种为10% - 20%，4种为40% - 49%。
热带植物调查、花粉采集、自身变应原制作、临床皮内试验及致敏原发现，不仅增加了热带致敏花粉自身变应原的种类，还提高了热带地区花粉症的特异性诊断。
