Chen H C, Ou S Y, Lai Y L
Department of Surgery, Mackay Memorial Hospital, Taipei, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1991 Apr;47(4):249-54.
This is a study of 11 patients who received combined surgery and irradiation for intractable hypertrophic scars and keloids. All of the patients received early post-operative (within 24 hours) irradiation with a 6-MeV electron beam and a total dose ranging from 1500-2100 rads in five to nine fractions after surgical excision of the lesions. The subjects were followed-up for over six months and the results are as follows: seven had a good response; three had a partial response; and one experienced a recurrence. The overall response rate was 90%, and no radiation injuries to the skin or delayed healing of the wound were noted. These preliminary outcomes are encouraging, especially for those patients who can not tolerate or have not responded well to other treatment programs.
这是一项针对11例因难治性增生性瘢痕和瘢痕疙瘩接受联合手术及放疗的患者的研究。所有患者在术后早期（24小时内）接受6兆电子伏电子束照射，病变手术切除后分五至九次给予的总剂量为1500 - 2100拉德。对这些受试者进行了超过六个月的随访，结果如下：七例反应良好；三例部分有效；一例复发。总有效率为90%，未观察到皮肤放射性损伤或伤口延迟愈合。这些初步结果令人鼓舞，尤其对于那些无法耐受或对其他治疗方案反应不佳的患者。
