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广泛瘢痕、增生性瘢痕和瘢痕疙瘩。

Wide spread scars, hypertrophic scars, and keloids.

作者信息

Rudolph R

出版信息

Clin Plast Surg. 1987 Apr;14(2):253-60.

PMID:3581659
Abstract

Patients with a wide scar may complain of having a "keloid," yet have a hypertrophic or a wide spread scar. The plastic surgeon should make the appropriate clinical diagnosis, because therapy varies depending on the condition present. A wide spread scar is best treated with excision and closure. A buried dermal flap may help to prevent recurrence, which is nevertheless likely to some degree. A hypertrophic scar can be distinguished from a keloid on clinical grounds. Although both may be red, nodular, and itchy, the keloid overgrows the original wound boundary and is much more likely to recur after surgical excision. Nonsurgical treatment of hypertrophic scars and keloids is similar, using repeated intralesional injections of Kenalog 40 mg per cc and sustained pressure on the lesion when possible. Surgical treatment differs for hypertrophic scars or keloids. Scar excision and closure, and selective Z-plasty, may be used in hypertrophic scars. In keloids, aggressive surgery is usually avoided, unless the lesion has a narrow pedicle. Surgery of keloids should be accompanied by intra- and postoperative Kenalog-40 injections, and on occasion by sustained pressure. Very large keloids may be resistant to medical management, and too aggressive for surgery owing to a high likelihood of recurrence. These difficult lesions serve as the impetus for continued biochemical and tissue culture research, seeking a biochemical means of control keloids.

摘要

有宽大瘢痕的患者可能会主诉有“瘢痕疙瘩”,但实际上是增生性瘢痕或宽大的扩散性瘢痕。整形外科医生应做出恰当的临床诊断,因为治疗方法会因现有病情的不同而有所差异。宽大的扩散性瘢痕最好通过切除和缝合来治疗。埋藏皮瓣可能有助于防止复发,不过仍有一定程度的复发可能性。增生性瘢痕可根据临床特征与瘢痕疙瘩相区分。虽然两者都可能发红、呈结节状且瘙痒,但瘢痕疙瘩会超出原始伤口边界生长,并且在手术切除后更易复发。增生性瘢痕和瘢痕疙瘩的非手术治疗方法相似,即反复进行每毫升含40毫克曲安奈德的病损内注射,并尽可能对病损施加持续压力。增生性瘢痕和瘢痕疙瘩的手术治疗方法有所不同。增生性瘢痕可采用瘢痕切除和缝合以及选择性Z成形术。对于瘢痕疙瘩,通常避免进行激进手术,除非病损有狭窄的蒂部。瘢痕疙瘩手术应在术中及术后注射曲安奈德-40,有时还需施加持续压力。非常大的瘢痕疙瘩可能对药物治疗有抵抗性,且由于复发可能性高而不适于进行激进手术。这些棘手的病损推动了持续的生化和组织培养研究,以寻求控制瘢痕疙瘩的生化方法。

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