Zhang Ya-jun, Zheng Hang-sheng, Xu Liang-ying, Li Jiang-ying
Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Zhongguo Zhong Yao Za Zhi. 2005 Nov;30(22):1794-6.
This paper reviews the lastest progress on oral prolonged-release preparation of traditional Chinese medicine. Four materials, include component, effective parts, single drug, and compound drugs of traditiong Chinese medicine, have been used to produce oral prolonged-release preparation. The main contents are study of preparation and evaluation of in vitro release. There are also some research works on integrative evaluation, pharmacokinetics and pharmacological activity of the prolonged-release preparation. It believes that the study on oral prolonged-release preparation of traditional Chinese medicine will have good prospect.
本文综述了中药口服缓释制剂的最新研究进展。制备中药口服缓释制剂所采用的原料有四类，包括中药的有效成分、有效部位、单味药、复方。主要内容是制剂研究和体外释放度评价。对于缓释制剂的综合评价、药代动力学及药理活性也有一些研究工作。认为中药口服缓释制剂的研究将具有良好的前景。
