Li Wen-Hao, He Ying
College of Pharmaceuticals and Biotechnology, Tianjin University, Tianjin 300072, China.
Zhongguo Zhong Yao Za Zhi. 2007 Mar;32(5):371-4.
Microparticle preparation, a new drug delivery system based on microencapsulation technique, includes micro-spheres and microcapsules. Recently, this new drug delivery system has been applied in developing new dosage forms for the traditional Chinese medicine (TCM). TCM microparticles can perform several sound characteristics and functions which are currently unavailable in TCM preparations, such as controlled release, effect of targeting, increasing bioavailability or low toxicity. This makes it possible that TCM may exert much higher therapeutic efficacy and show lower side-effects as well. Although the studies on TCM microparticles are still in the beginning stage, microparticle preparation of TCM has given rise to comprehensive attention and will have a wonderful prospect. The progress in this field is reviewed in this article.
微粒制剂是一种基于微囊化技术的新型药物递送系统，包括微球和微胶囊。近年来，这种新型药物递送系统已被应用于开发中药新剂型。中药微粒具有多种目前中药制剂所不具备的良好特性和功能，如控释、靶向作用、提高生物利用度或低毒性。这使得中药有可能发挥更高的治疗效果，且副作用也更低。尽管对中药微粒的研究仍处于起步阶段，但中药微粒制剂已引起广泛关注，并将拥有广阔前景。本文综述了该领域的进展。
