Enokibori T, Katsura A, Watanabe K, Kato H, Mori A
Department of Thoracic Surgery, Rakuwakai-Otowa Hospital, Kyoto, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1991 Apr;39(4):485-91.
A 72-year-old woman was admitted for cough and dyspnea. Bronchofiberscopy examination revealed lung cancer at the right main bronchus. Plain chest X-ray and chest CT revealed that the tumor had invaded to the mediastinum and esophagography demonstrated stenosis of the thoracic esophagus without fistula. Because pulmonary resection was contraindicated, chemotherapy for lung cancer was initiated. Complete response was noted, but an esophago-pleural fistula developed as a consequence of chemotherapy. After intrathoracic tube drainage, a permanent endoesophageal tube was inserted through a small incision in the stomach under general anesthesia. However, it migrated into the thoracic empyema after 4-postoperative days. Because the lung cancer was well-controlled, a second operation to reconstruct the esophagus was performed without resection of the thoracic esophagus or fistula. After the operation, thoracic empyema was washed out with povidone iodine and pure alcohol. The chest tube was removed 3 months after the second operation. We conclude that in cases of esophago-pleural fistula caused by chemotherapy for lung cancer, if complete response to chemotherapy is noted, reconstruction of the esophagus should be considered.
一名72岁女性因咳嗽和呼吸困难入院。支气管纤维镜检查显示右主支气管肺癌。胸部X线平片和胸部CT显示肿瘤已侵犯纵隔,食管造影显示胸段食管狭窄但无瘘管形成。由于肺切除术为禁忌,遂开始进行肺癌化疗。化疗后达到完全缓解,但化疗导致了食管胸膜瘘。胸腔闭式引流后,在全身麻醉下经胃小切口插入永久性食管内导管。然而,术后4天导管移入胸腔脓胸。由于肺癌得到良好控制,在未切除胸段食管或瘘管的情况下进行了第二次食管重建手术。术后,用聚维酮碘和纯酒精冲洗胸腔脓胸。第二次手术后3个月拔除胸管。我们得出结论,对于肺癌化疗引起的食管胸膜瘘病例,如果化疗达到完全缓解,应考虑食管重建。