人类细胞色素c氧化酶亚基VIb基因最后一个外显子的核苷酸序列及其侧翼区域。

Nucleotide sequence of the last exon of the gene for human cytochrome c oxidase subunit VIb and its flanking regions.

作者信息

Taanman J W, Schrage C, Bokma E, Reuvekamp P, Agsteribbe E, De Vries H

机构信息

Laboratory of Physiological Chemistry, University of Groningen, The Netherlands.

出版信息

Biochim Biophys Acta. 1991 Jun 13;1089(2):283-5. doi: 10.1016/0167-4781(91)90027-j.

DOI:10.1016/0167-4781(91)90027-j

PMID:1647217

Abstract

A human genomic clone encompassing the last exon of the gene for cytochrome c oxidase subunit VIb and a human genomic clone containing the most distal end of this gene were characterized. The last exon of the gene codes for the 17 C-terminal amino acid residues of the subunit and the 3' noncoding region. Downstream from the gene we found a single base difference between the DNA sequences of the two genomic clones. An inverted Alu dimer repeat was identified further downstream.

摘要

对一个包含细胞色素c氧化酶亚基VIb基因最后一个外显子的人类基因组克隆以及一个包含该基因最远端的人类基因组克隆进行了表征。该基因的最后一个外显子编码该亚基的17个C末端氨基酸残基以及3'非编码区。在该基因下游，我们发现两个基因组克隆的DNA序列之间存在一个单碱基差异。在更下游还鉴定出一个反向Alu二聚体重复序列。