Assignment of the gene coding for human cytochrome c oxidase subunit VIb to chromosome 19, band q13.1, by fluorescence in situ hybridisation.
作者信息
Taanman J W, van der Veen A Y, Schrage C, de Vries H, Buys C H
机构信息
Laboratory of Physiological Chemistry, University of Groningen, The Netherlands.
出版信息
Hum Genet. 1991 Jul;87(3):325-7. doi: 10.1007/BF00200913.
PMID:1650756
Abstract
A cloned, 40 kb, genomic DNA fragment, containing the last exon of the gene for human cytochrome c oxidase subunit VIb and its flanking sequences, was used as a probe to localize the subunit VIb gene on human metaphase chromosomes. The probe was labelled with Bio-11-dUTP and detected by fluorescence. Subsequent R-banding indicated that the cytochrome c oxidase subunit VIb gene is localized in band 19q13.1, extending the evidence that the human nuclear genes of cytochrome c oxidase are not clustered.
摘要
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