Moebus Susanne, Lehmann Nils, Bödeker Wolfgang, Jöckel Karl-Heinz
Institute for Medical Informatics, Biometry and Epidemiology, Medical Faculty, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.
BMC Public Health. 2006 Feb 12;6:28. doi: 10.1186/1471-2458-6-28.
The popularity of complementary and alternative medicine (CAM) has led to a growing amount of research in this area. All the same little is known about the effects of these special treatments in every-day practice of primary care, delivered by general practitioners within the health insurance system. From 1994 to 2000 more than 20 German Company health insurances initiated the first model project on CAM according to the German social law. Aim of this contribution is to investigate the effectiveness of multi-modal CAM on chronic diseases within primary health care.
A long-term prospective intermittent study was conducted including 44 CAM practitioners and 1221 self-selected chronically ill patients (64% women) of whom 441 were employed. Main outcome measure is sick-leave, controlled for secular trends and regression-to-the mean and self-perceived health status.
Sick-leave per year of 441 patients at work increased from 22 (SD +/- 45.2) to 31 (+/- 61.0) days within three years prior to intervention, and decreased to 24 (+/- 55.6) in the second year of treatment, sustaining at this level in the following two years. Detailed statistical analysis show that this development exceeds secular trends and the regression-toward-the-mean effect. Sick-leave reduction was corroborated by data on self-reported improvement of patients' health status.
Results of this longterm observational study show a reduction of sick leave in chronically ill patients after a complex multimodal CAM intervention. However, as this is an uncontrolled observational study efficacy of any specific CAM treatment can not be proven. The results might indicate an general effectiveness of CAM in primary care, worthwhile further investigations. Future studies should identify the most suitable patients for CAM practices, the most appropriate and safe treatments, provide information on the magnitude of the effects to facilitate subsequent definitive randomised controlled studies that will help to position complementary and alternative medicine in health care.
补充和替代医学(CAM)的普及促使该领域的研究日益增多。尽管如此,对于这些特殊治疗在医疗保险体系内由全科医生提供的初级保健日常实践中的效果,人们所知甚少。1994年至2000年期间,超过20家德国企业健康保险公司根据德国社会法启动了首个补充和替代医学示范项目。本文的目的是研究多模式补充和替代医学在初级卫生保健中对慢性病的有效性。
进行了一项长期前瞻性间歇性研究,纳入了44名补充和替代医学从业者以及1221名自我选择的慢性病患者(64%为女性),其中441人有工作。主要结局指标是病假天数,并对长期趋势、均值回归和自我感知的健康状况进行了控制。
441名在职患者的年病假天数在干预前三年内从22天(标准差±45.2)增加到31天(±61.0),在治疗的第二年降至24天(±55.6),并在随后两年维持在这一水平。详细的统计分析表明,这一变化超过了长期趋势和均值回归效应。患者自我报告的健康状况改善数据证实了病假天数的减少。
这项长期观察性研究的结果表明,复杂的多模式补充和替代医学干预后,慢性病患者的病假天数减少。然而,由于这是一项非对照观察性研究,无法证明任何特定补充和替代医学治疗的疗效。结果可能表明补充和替代医学在初级保健中具有总体有效性,值得进一步研究。未来的研究应确定最适合接受补充和替代医学治疗的患者、最合适和安全的治疗方法,提供有关效果大小的信息,以便开展后续确定性随机对照研究,这将有助于补充和替代医学在医疗保健中的定位。