马疱疹病毒1型及其他具有兽医重要性的疱疹病毒的免疫逃逸
Immune escape of equine herpesvirus 1 and other herpesviruses of veterinary importance.
作者信息
van der Meulen Karen M, Favoreel Herman W, Pensaert Maurice B, Nauwynck Hans J
机构信息
Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium.
出版信息
Vet Immunol Immunopathol. 2006 May 15;111(1-2):31-40. doi: 10.1016/j.vetimm.2006.01.006. Epub 2006 Feb 10.
Equine herpesvirus (EHV)-1 is a pathogen of horses, well known for its ability to induce abortion and nervous system disorders. Clinical signs may occur despite the presence of a virus-specific immune response in the horse. The current review will summarize the research, on how, EHV-1-infected cells can hide from recognition by the immune system. Research findings on immune evasion of EHV-1 will be compared with those of other herpesviruses of veterinary importance.
马疱疹病毒1型（EHV-1）是马的一种病原体，以其诱发流产和神经系统疾病的能力而闻名。尽管马体内存在病毒特异性免疫反应，但仍可能出现临床症状。本综述将总结关于EHV-1感染细胞如何躲避免疫系统识别的研究。将EHV-1免疫逃逸的研究结果与其他具有兽医重要性的疱疹病毒的研究结果进行比较。
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