氢呼气试验的应用与滥用
Use and abuse of hydrogen breath tests.
作者信息
Simrén M, Stotzer P-O
机构信息
Section of Gastroenterology and Hepatology, Department of Internal Medicine, Sahlgrenska University Hospital, S-41345 Göteborg, Sweden.
出版信息
Gut. 2006 Mar;55(3):297-303. doi: 10.1136/gut.2005.075127.
Abstract
Hydrogen breath tests are widely used to explore the pathophysiology of functional gastrointestinal disorders. Small intestinal bacterial overgrowth and carbohydrate malabsorption are disorders detected by these tests that have been proposed to be of great importance for symptoms in, for instance, irritable bowel syndrome. However, conclusions drawn from these studies are highly controversial and divergent results exist. There is also an extensive use of these tests in clinical practice with difficulties regarding interpretation of the tests and sometimes erroneous conclusions. The limitations and pitfalls of these tests will be reviewed in this article, and hopefully the occasional abuse of these tests can be turned into proper clinical and scientific use instead in the future.
摘要
氢呼气试验被广泛用于探究功能性胃肠疾病的病理生理学。小肠细菌过度生长和碳水化合物吸收不良是通过这些试验检测出的疾病，有人认为这些疾病对于诸如肠易激综合征等病症的症状具有重要意义。然而，从这些研究得出的结论极具争议性，且存在分歧性结果。这些试验在临床实践中也被广泛应用，但在试验解读方面存在困难，有时还会得出错误结论。本文将对这些试验的局限性和陷阱进行综述，希望未来能将这些试验偶尔的滥用转变为恰当的临床和科学应用。
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