Blanco Susana, Rodríguez Eloy, Galache Cristina, Cosme Alvarez-Cuesta César, Nosti Dolores
Servicio de Dermatología, Hospital de Cabueñes, Cabueñes s/n, 33394 Gijón, Spain.
Actas Dermosifiliogr. 2005 May;96(4):241-4. doi: 10.1016/s0001-7310(05)73077-5.
"Mechanic's hands" are a characteristic cutaneous sign of idiopathic inflammatory myositis. We describe the case of a 61-year-old male patient who was diagnosed with idiopathic polymyositis and non-specific interstitial lung disease in 1999, and three years later developed scaly, fissured hyperkeratotic lesions on the lateral and palmar surfaces of the first three fingers of both hands, with little pruritus. The presence of the anti-Jo-1 antisynthetase antibody in the patient's serum, the finding of skin lesions characteristic of "mechanic's hands" and the patient's other systemic clinical manifestations made it possible to establish the diagnosis of "antisynthetase syndrome."
“技工手”是特发性炎性肌病的一种特征性皮肤表现。我们报告一例61岁男性患者，该患者于1999年被诊断为特发性多肌炎和非特异性间质性肺病，三年后双手前三指的外侧和掌面出现鳞屑状、有裂隙的角化过度性皮损，伴轻度瘙痒。患者血清中抗Jo-1抗合成酶抗体的存在、“技工手”特征性皮肤损害的发现以及患者的其他全身临床表现，使得“抗合成酶综合征”的诊断得以确立。
