Vanderwerker Lauren C, Jacobs Selby C, Parkes Colin Murray, Prigerson Holly G
Center for Psycho-oncology and Palliative Care Research, Dana Farber Cancer Institute, and Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 022115, USA.
J Nerv Ment Dis. 2006 Feb;194(2):121-3. doi: 10.1097/01.nmd.0000198146.28182.d5.
Recent studies have suggested that the vulnerability to complicated grief (CG) may be rooted in insecure attachment styles developed in childhood. The aim of this study was to examine the etiologic relevance of childhood separation anxiety (CSA) to the onset of CG relative to major depressive disorder, posttraumatic stress disorder, and generalized anxiety disorder in bereaved individuals. The Structured Clinical Interview for the DSM-IV, Inventory of Complicated Grief-Revised, and CSA items from the Panic Agoraphobic Spectrum Questionnaire were administered to 283 recently bereaved community-dwelling residents at an average of 10.6 months postloss. CSA was significantly associated with CG (OR = 3.2; 95% CI, 1.2-8.9), adjusting for sex, level of education, kinship relationship to the deceased, prior history of psychiatric disorder, and history of childhood abuse. CSA was not significantly associated with major depressive disorder, posttraumatic stress disorder, or generalized anxiety disorder.
近期研究表明，复杂悲伤（CG）的易感性可能源于童年时期形成的不安全依恋模式。本研究的目的是检验童年分离焦虑（CSA）与丧亲个体中CG的发病相对于重度抑郁症、创伤后应激障碍和广泛性焦虑障碍的病因学相关性。对283名近期丧亲的社区居民进行了《精神疾病诊断与统计手册》第四版的结构化临床访谈、修订版复杂悲伤量表以及惊恐广场恐怖谱系问卷中的CSA项目，平均丧亲时间为10.6个月。在对性别、教育程度、与死者的亲属关系、既往精神疾病史和童年虐待史进行调整后，CSA与CG显著相关（OR = 3.2；95%CI，1.2 - 8.9）。CSA与重度抑郁症、创伤后应激障碍或广泛性焦虑障碍无显著相关性。
