低功率激光照射对使红细胞膜上附着的血红蛋白脱离的影响。

Effect of low power laser irradiation on disconnecting the membrane-attached hemoglobin from erythrocyte membrane.

作者信息

Mi X Q, Chen J Y, Zhou L W

机构信息

Department of Physics, Fudan University, Shanghai 200433, China; State Key Laboratory of Applied Surface Physics, Fudan University, Shanghai, China.

出版信息

J Photochem Photobiol B. 2006 May 1;83(2):146-50. doi: 10.1016/j.jphotobiol.2005.12.018. Epub 2006 Feb 14.

DOI:10.1016/j.jphotobiol.2005.12.018

PMID:16481193

Abstract

In our previous study we found that low power laser irradiation improved the erythrocyte deformability, but the mechanism is unclear. The membrane-attached hemoglobin (Hbm) may be one of the determining factors for the erythrocyte deformability. We report here for the first time, that laser irradiation can reduce the Hbm contents in pig's erythrocytes, providing the explanation for the improvement of erythrocyte deformability. The decrease of the Hbm was proportional to the irradiation dose, but the relative change of Hbm was saturated around 35%. The 532 nm laser was more efficient at lowering Hbm than the 632.8 nm laser, consistent with the absorption spectrum of Hbm.

摘要

在我们之前的研究中，我们发现低功率激光照射可改善红细胞变形性，但其机制尚不清楚。膜结合血红蛋白（Hbm）可能是红细胞变形性的决定因素之一。我们在此首次报告，激光照射可降低猪红细胞中的Hbm含量，这为红细胞变形性的改善提供了解释。Hbm的降低与照射剂量成正比，但Hbm的相对变化在35%左右达到饱和。532nm激光在降低Hbm方面比632.8nm激光更有效，这与Hbm的吸收光谱一致。