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急性胰腺炎后的长期复发率和死亡率。

Long-term recurrence and death rates after acute pancreatitis.

作者信息

Lund Helle, Tønnesen Hanne, Tønnesen Maja Hanne, Olsen Ole

机构信息

Department of Surgical Gastroenterology D, Glostrup Hospital, University of Copenhagen and Clinical Unit of Health Promotion, Bispebjerg Hospital, Denmark.

出版信息

Scand J Gastroenterol. 2006 Feb;41(2):234-8. doi: 10.1080/00365520510024133.

Abstract

OBJECTIVE

The aim of this study was to compare long-term recurrence and death rates after a first episode of acute pancreatitis in patients with and without gallstones. Additionally, it was of interest to find out if there were factors predictive of readmission or death.

MATERIAL AND METHODS

Over a period of 3 years (1995 to 1998), 155 patients admitted with a first attack of acute pancreatitis were included in the study. They followed a specific protocol (ultrasound within 24 h, laboratory tests, Ranson scoring and patients with severe pancreatitis computed tomography scans). In gallstones, pancreatitis, either ERCP or cholecystectomy, was performed at admission or in the case of the latter within 4 weeks. A follow-up was done in January 2002.

RESULTS

Forty-one percent of the patients without gallstones were readmitted to hospital during the period of follow-up compared to 10% in the group of patients with gallstones. Using multivariate analysis, no factors were significantly predictive of readmission.

CONCLUSIONS

We found an identical mortality rate of 15% in the two groups, the only predictive factor being age.

摘要

目的

本研究旨在比较有胆结石和无胆结石的急性胰腺炎患者首次发作后的长期复发率和死亡率。此外,找出是否存在预测再次入院或死亡的因素也很有意义。

材料与方法

在3年期间(1995年至1998年),155例因首次急性胰腺炎发作入院的患者纳入本研究。他们遵循特定方案(24小时内进行超声检查、实验室检查、兰森评分,重症胰腺炎患者进行计算机断层扫描)。对于胆结石性胰腺炎患者,入院时或后者在4周内进行内镜逆行胰胆管造影(ERCP)或胆囊切除术。2002年1月进行随访。

结果

随访期间,无胆结石患者中有41%再次入院,而胆结石患者组为10%。采用多变量分析,没有因素能显著预测再次入院。

结论

我们发现两组的死亡率均为15%,唯一的预测因素是年龄。

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