Leena Mattila, Ville Valtonen, Veli-Jukka Anttila
Department of Medicine, Division of Infectious Diseases, Helsinki University Central Hospital, Finland.
Scand J Gastroenterol. 2006 Feb;41(2):242-4. doi: 10.1080/00365520500328113.
Reactivation of varicella zoster virus (VZV) is a common event after stem cell transplantation (SCT). When activated in the abdominal cavity, the infection may be life threatening. Visceral presentation with VZV infection is uncommon, although probably an under-diagnosed event in post-SCT patients. The interval from onset of abdominal pain to the development of skin eruptions may delay the initiation of specific antiviral therapy and symptoms may be incorrectly diagnosed as surgical disease or graft-versus-host disease. We describe the case of a 53-year-old man who had undergone stem cell autograft for multiple myeloma and developed visceral VZV infection with hepatitis, melaena and subileus 7 months later.
水痘带状疱疹病毒（VZV）再激活是干细胞移植（SCT）后常见的情况。当在腹腔内激活时，感染可能危及生命。VZV感染的内脏表现并不常见，尽管在SCT后患者中可能是诊断不足的情况。从腹痛发作到皮疹出现的间隔可能会延迟特异性抗病毒治疗的开始，症状可能被错误地诊断为外科疾病或移植物抗宿主病。我们描述了一名53岁男性的病例，他因多发性骨髓瘤接受了自体干细胞移植，7个月后发生了伴有肝炎、黑便和不全肠梗阻的内脏VZV感染。
