Mertens E
Rockefeller University, New York, NY 10021.
FEBS Lett. 1991 Jul 8;285(1):1-5. doi: 10.1016/0014-5793(91)80711-b.
Recent evidence indicates that in as diverse organisms as unicellular eukaryotes, higher plants and prokaryotes, anaerobic glycolysis relies on a pyrophosphate-dependent phosphofructokinase instead of the classical ATP-dependent enzyme. This difference in phosphoryl donor specificity does not necessarily reflect a primitive metabolism, as thought earlier, but could rather be the result of convergent evolution, fostered by the energetic advantage conferred to the cell when glycolysis is the sole source of ATP.
最近的证据表明，在单细胞真核生物、高等植物和原核生物等多种生物中，无氧糖酵解依赖于一种焦磷酸依赖性磷酸果糖激酶，而非传统的ATP依赖性酶。磷酸供体特异性的这种差异并不一定如之前所想的那样反映了一种原始的代谢方式，而更有可能是趋同进化的结果，当糖酵解是ATP的唯一来源时，这种趋同进化受到细胞所获得的能量优势的推动。
