Huhman K L, Moore T O, Ferris C F, Mougey E H, Meyerhoff J L
Department of Medical Neurosciences, Walter Reed Army Institute of Research, Washington, D.C. 20307-5100.
Horm Behav. 1991 Jun;25(2):206-16. doi: 10.1016/0018-506x(91)90051-i.
The purpose of the present study was to characterize the hormonal response of dominant and submissive male hamsters to acute and repeated exposure to social conflict. We found that submissive, but not dominant, males exhibited elevated plasma levels of adrenocorticotropin (ACTH), cortisol, and beta-endorphin (beta-EP) following one exposure to an agonistic encounter. After five exposures to a dominant opponent, submissive males showed smaller, but still significant, elevations in these plasma hormones. After nine exposures, submissive hamsters showed significant elevations only in plasma ACTH and beta-EP. Plasma testosterone was significantly suppressed in submissive males that fought nine times. We conclude that hamsters are a useful species with which to study the neuroendocrine correlates of social behavior.
本研究的目的是描述处于支配地位和从属地位的雄性仓鼠在急性和反复暴露于社会冲突时的激素反应。我们发现，从属雄性仓鼠（而非处于支配地位的雄性仓鼠）在经历一次争斗性遭遇后，其血浆促肾上腺皮质激素（ACTH）、皮质醇和β-内啡肽（β-EP）水平升高。在与占主导地位的对手进行五次对抗后，从属雄性仓鼠的这些血浆激素水平升高幅度较小，但仍具有显著差异。在经历九次对抗后，从属仓鼠仅血浆ACTH和β-EP水平显著升高。在进行了九次争斗的从属雄性仓鼠中，血浆睾酮水平受到显著抑制。我们得出结论，仓鼠是研究社会行为神经内分泌相关性的有用物种。
