Drake E, Drake M, Bird J, Russell R
Nuffield Department of Anaesthetics, John Radcliffe Hospital, Oxford, UK.
Int J Obstet Anesth. 2006 Apr;15(2):115-23. doi: 10.1016/j.ijoa.2005.10.010. Epub 2006 Feb 20.
There has been a reluctance to use regional blocks for women with multiple sclerosis as effects on the course of the disease are unclear. We assessed the views of UK consultant obstetric anaesthetists regarding management of women with multiple sclerosis.
Following Obstetric Anaesthetists' Association approval a questionnaire was sent to UK consultant members. Opinions were sought on antenatal assessment, labour analgesia, anaesthesia for elective and emergency caesarean section, and modification in technique for those with multiple sclerosis. Enquiries were made of postnatal problems ascribed to regional blocks.
Of the 592 replies analysed, 91% of respondents had seen fewer than 10 cases of multiple sclerosis in the past 10 years. Antenatal assessment was recommended by many with postnatal relapse most commonly discussed (64%). Many highlighted the need for informed consent and minimising local anaesthetic dose. For labour analgesia 79% would perform a regional block; a further 20% would do so in certain circumstances. For elective caesarean section, epidural rather than spinal anaesthesia was preferred by 4%; 2% would not use a regional block, preferring general anaesthesia. For emergency caesarean section with time only for single-shot spinal, 3% would give a general anaesthetic. Deterioration of symptoms after delivery were reported by 20% with 3% attributing symptoms such as prolonged block, leg weakness, bladder dysfunction and postnatal relapse to regional blocks.
Most UK anaesthetists would perform regional blocks for labour and caesarean section in multiple sclerosis, although the experience of each anaesthetist is limited. Many emphasised the need for thorough pre-assessment and informed consent.
由于区域阻滞对多发性硬化症病程的影响尚不清楚,一直以来人们都不太愿意将其用于患有多发性硬化症的女性。我们评估了英国产科麻醉顾问医生对于患有多发性硬化症女性的管理意见。
在获得产科麻醉医师协会批准后,向英国顾问医生成员发送了一份调查问卷。征求了关于产前评估、分娩镇痛、择期和急诊剖宫产麻醉以及针对患有多发性硬化症患者的技术调整方面的意见。还询问了归因于区域阻滞的产后问题。
在分析的592份回复中,91%的受访者在过去10年中见过少于10例多发性硬化症病例。许多人建议进行产前评估,其中最常讨论的是产后复发(64%)。许多人强调需要获得知情同意并尽量减少局部麻醉剂剂量。对于分娩镇痛,79%的人会进行区域阻滞;另外20%的人会在某些情况下进行。对于择期剖宫产,4%的人更喜欢硬膜外麻醉而非脊髓麻醉;2%的人不会使用区域阻滞,更倾向于全身麻醉。对于仅有单次脊髓麻醉时间的急诊剖宫产,3%的人会选择全身麻醉。20%的人报告了产后症状恶化,3%的人将诸如阻滞时间延长、腿部无力、膀胱功能障碍和产后复发等症状归因于区域阻滞。
大多数英国麻醉医生会对患有多发性硬化症的女性进行分娩和剖宫产的区域阻滞,尽管每位麻醉医生的经验有限。许多人强调需要进行全面的术前评估和获得知情同意。