Gordon Kenneth B, Ruderman Eric M
Division of Dermatology, Evanston Northwestern Healthcare, Skokie, Illinois 60077, USA.
J Am Acad Dermatol. 2006 Mar;54(3 Suppl 2):S85-91. doi: 10.1016/j.jaad.2005.10.052.
Psoriatic arthritis is a common inflammatory arthritis associated with psoriasis, occurring in 5% to 40% of patients with cutaneous disease. Recently, there has been an increased appreciation of the need to use an integrated approach to these 2 diseases, considering both entities when determining therapeutic choices. In this review, the available therapeutic options for psoriatic arthritis are considered, along with the potential benefit that these medications may have for cutaneous psoriasis. Finally, a conceptual model for the therapy of psoriasis and psoriatic arthritis, the Four Quadrant Model, is presented as a simplified framework to use when considering treatment for psoriatic disease.
银屑病关节炎是一种与银屑病相关的常见炎性关节炎，见于5%至40%的皮肤病患者。最近，人们越来越认识到需要对这两种疾病采用综合方法，在确定治疗选择时要同时考虑这两种情况。在本综述中，我们考虑了银屑病关节炎可用的治疗选择，以及这些药物对皮肤银屑病可能具有的潜在益处。最后，提出了一种银屑病和银屑病关节炎治疗的概念模型——四象限模型，作为在考虑银屑病治疗时使用的简化框架。
