Clinica Medica, Dipartimento Scienze Cliniche e Molecolari, Università Politecnica delle Marche, Via Tronto 10/A, 60126, Ancona, Italy.
Clinica Dermatologica, Azienda Ospedaliero-Universitaria "Umberto I-G.M. Lancisi-G. Salesi", Ancona, 60020, Italy.
Clin Rheumatol. 2018 Oct;37(10):2741-2749. doi: 10.1007/s10067-018-4238-4. Epub 2018 Jul 29.
Psoriatic arthritis (PsA) is a chronic inflammatory autoimmune arthritis, occurring in patients with psoriasis (Pso), that may affect the whole musculoskeletal system but also nails, eye, and gastrointestinal tract. Dermatologists and rheumatologists usually manage Pso and PsA separately, but early diagnosis and integrated management could achieve better outcomes of both skin and musculoskeletal manifestations, thus improving the health-related quality of life (HRQoL) of patients. In this work, we have described a model of integrated dermo-rheumatologic approach for the early diagnosis of PsA and to present the outcomes of the multidisciplinary management of PsA patients after 48 weeks of follow-up. Pso patients complaining musculoskeletal symptoms were enrolled in a DErmo-Rheumatologic Clinic (DERC) in order to screen, classify, and treat patients with PsA, employing an operative working procedure and a specific flowchart. The integrated dermatologic and rheumatologic management of PsA patients allowed a prompt establishment of the diagnosis and the best therapeutic approach in these patients, with a significant improvement of skin and articular diseases and, eventually, a consistent amelioration of HRQoL. Dermatologists and rheumatologists usually manage the "psoriatic disease" in separated outpatient clinics. In our study, we have demonstrated that a combined DERC, by means of a tight cooperation between the dermatologist and the rheumatologist, which use a specific working procedure and treatment flowchart, may achieve the optimal clinical management of these patients, with a consistent clinical remission of the disease and a significant amelioration of the HRQoL.
银屑病关节炎(PsA)是一种慢性炎症性自身免疫性关节炎,发生于银屑病(Pso)患者中,可能影响整个肌肉骨骼系统,但也可能影响指甲、眼睛和胃肠道。皮肤科医生和风湿病医生通常分别管理 Pso 和 PsA,但早期诊断和综合管理可以实现皮肤和肌肉骨骼表现的更好结果,从而提高患者的健康相关生活质量(HRQoL)。在这项工作中,我们描述了一种综合的皮肤科-风湿病方法模型,用于早期诊断 PsA,并介绍了 48 周随访后对 PsA 患者进行多学科管理的结果。有肌肉骨骼症状的 Pso 患者被纳入 DErmo-Rheumatologic 诊所(DERC),以筛查、分类和治疗 PsA 患者,采用手术操作程序和特定流程图。对 PsA 患者进行综合的皮肤科和风湿病管理,可以及时明确诊断,并为这些患者提供最佳治疗方法,显著改善皮肤和关节疾病,最终显著改善 HRQoL。皮肤科医生和风湿病医生通常在分开的门诊诊所管理“银屑病疾病”。在我们的研究中,我们证明了联合 DERC 通过皮肤科医生和风湿病医生之间的紧密合作,使用特定的操作程序和治疗流程图,可以实现对这些患者的最佳临床管理,使疾病持续临床缓解,并显著改善 HRQoL。