低温环境下血管的热膨胀，第二部分：使用VS55、DP6和7.05 M二甲基亚砜进行玻璃化
Thermal expansion of blood vessels in low cryogenic temperatures, Part II: Vitrification with VS55, DP6, and 7.05 M DMSO.
作者信息
Rios Jorge L Jimenez, Rabin Yoed
机构信息
Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.
出版信息
Cryobiology. 2006 Apr;52(2):284-94. doi: 10.1016/j.cryobiol.2005.12.006. Epub 2006 Feb 20.
Abstract
As part of the ongoing effort to study the mechanical behavior of biological materials in cryopreservation processes, the current study focuses on thermal expansion during vitrification (vitreous in Latin means glassy). A new device is utilized in this study, which has been described in detail in the companion paper (Part I). The current study (Part II) focuses on measurements of vitrified blood vessels permeated with the cryoprotectants VS55, DP6, and DMSO. Data analysis in this study includes polynomial approximation of experimental results in the lower part of the cryogenic temperature range, where the material behaves as solid over a practical time scale. The study further includes a unified thermal expansion analysis throughout the entire cryogenic temperature range by compiling the current results with previously reported data. Finally, analysis of the glass transition temperature, based on thermal strain data is presented.
摘要
作为研究生物材料在冷冻保存过程中力学行为的持续努力的一部分，当前研究聚焦于玻璃化过程中的热膨胀（“玻璃态”在拉丁语中意为“似玻璃的”）。本研究使用了一种新装置，其在配套论文（第一部分）中有详细描述。当前研究（第二部分）聚焦于用冷冻保护剂VS55、DP6和二甲基亚砜渗透的玻璃化血管的测量。本研究中的数据分析包括在低温温度范围下部对实验结果进行多项式近似，在该温度范围内材料在实际时间尺度上表现为固体。该研究还通过将当前结果与先前报告的数据汇总，在整个低温温度范围内进行统一的热膨胀分析。最后，基于热应变数据给出了玻璃化转变温度的分析。
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