Başmak Hikmet, Niyaz Leyla, Sahin Afsun, Erol Nazmiye, Gürsoy Haluk H
Department of Ophthalmology, Eskişehir Osmangazi University Medical Faculty, Meselik, Turkey.
Eur J Ophthalmol. 2010 Jul-Aug;20(4):752-5. doi: 10.1177/112067211002000417.
Timely screening of premature babies is an important initial step in the management of retinopathy of prematurity (ROP) as earlier treatment results in improved visual prognosis. Screening criteria for ROP currently recommended by the American Academy of Pediatrics may not be applicable in developing countries. The aim of the present study is to find out the incidence of ROP in infants with a gestational age (GA) of > or = 32 weeks in Eskisehir, Turkey, to provide information to assist in determining screening criteria.
A total of 96 infants with a GA of 32-35 weeks who were referred for ROP between January 1, 2004, and December 31, 2008, were studied. ROP screening, follow-up, and appropriate therapies were applied.
During ROP screening, there were 42 of 96 (43.8%) infants with no ROP. A total of 54/96 (56.2%) infants were noted to have ROP. Among all infants, 7 (7.3%) had threshold ROP. Two infants with threshold disease were born at the 32nd, 2 at the 33rd, and 3 at the 34th week of gestation. The mean birthweight was 1857.9 (range 1060-3200) grams. CONCLUSIONS. In our study, it was found that more mature infants may also develop threshold ROP and require early treatment. After more information is gained and widespread screening, screening protocols covering more mature infants can be designed especially for developing countries.
及时筛查早产儿是早产儿视网膜病变（ROP）管理的重要初始步骤，因为早期治疗可改善视觉预后。美国儿科学会目前推荐的ROP筛查标准可能不适用于发展中国家。本研究的目的是查明土耳其埃斯基谢希尔胎龄（GA）≥32周婴儿的ROP发病率，以提供信息协助确定筛查标准。
对2004年1月1日至2008年12月31日期间因ROP转诊的96例GA为32 - 35周的婴儿进行了研究。进行了ROP筛查、随访及适当治疗。
在ROP筛查期间，96例婴儿中有42例（43.8%）无ROP。共54/96（56.2%）例婴儿被发现患有ROP。所有婴儿中，7例（7.3%）患有阈值ROP。2例阈值疾病婴儿在孕32周出生，2例在孕33周出生，3例在孕34周出生。平均出生体重为1857.9（范围1060 - 3200）克。结论。在我们的研究中，发现胎龄较大的婴儿也可能发生阈值ROP并需要早期治疗。在获取更多信息并广泛筛查后，可专门为发展中国家设计涵盖胎龄较大婴儿的筛查方案。
