Gouveris H, Hansen T, Franke K
Universitäts-HNO-Klinik, Johannes-Gutenberg-Universität Mainz, Mainz.
Mund Kiefer Gesichtschir. 2006 Mar;10(2):122-5. doi: 10.1007/s10006-006-0673-5.
A patient with swelling of the left parotid gland of four-months' duration, sicca syndrome (xerophthalmia and xerostomia) and a history of progressive systemic sclerosis with an incomplete form of the CREST syndrome was referred to our department. On ultrasound a parotid mass of reduced echogenicity without any enlarged cervical lymph nodes was found. Ultrasonographically guided fine-needle biopsy could not provide any definitive diagnosis. After partial parotidectomy with complete tumor removal the histologic exam showed an extramedullary plasmacytoma with concurrent non-necrotizing granulomatous sialadenitis of the parotid gland. Complete systemic work-up excluded multiple myeloma, leukemia, lymphoma and sarcoidosis. Post-operative radiotherapy of the left parotid region and left neck including the supraclavicular lymph node area was performed. Six months after surgery an aggressive B-cell non-Hodgkin's lymphoma was diagnosed.
一位左侧腮腺肿大持续四个月、患有干燥综合征（干眼症和口干症）且有进行性系统性硬化症病史（CREST综合征不完全型）的患者被转诊至我科。超声检查发现腮腺有一个低回声肿块，颈部淋巴结无肿大。超声引导下细针穿刺活检未能提供明确诊断。在进行部分腮腺切除并完整切除肿瘤后，组织学检查显示为髓外浆细胞瘤，同时伴有腮腺非坏死性肉芽肿性涎腺炎。全面的全身检查排除了多发性骨髓瘤、白血病、淋巴瘤和结节病。对左侧腮腺区域和左侧颈部包括锁骨上淋巴结区域进行了术后放疗。术后六个月诊断出侵袭性B细胞非霍奇金淋巴瘤。
