自身免疫性胰腺炎中胰腺和胆管的受累情况。
Involvement of pancreatic and bile ducts in autoimmune pancreatitis.
作者信息
Kamisawa Terumi, Tu Yuyang, Egawa Naoto, Nakajima Hitoshi, Tsuruta Kouji, Okamoto Atsutake
机构信息
Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, 3-18-22 Honkomagome, Bunkyo-ku, Tokyo 113-8677, Japan.
出版信息
World J Gastroenterol. 2006 Jan 28;12(4):612-4. doi: 10.3748/wjg.v12.i4.612.
AIM
To examine the involvement of the pancreatic and bile ducts in patients with autoimmune pancreatitis.
METHODS
Clinical and cholangiopancreatographic findings of 28 patients with autoimmune pancreatitis were evaluated. For the purposes of this study, the pancreatic duct system was divided into three portions: the ventral pancreatic duct; the head portion of the dorsal pancreatic duct; and the body and tail of the dorsal pancreatic duct.
RESULTS
Both the ventral and dorsal pancreatic ducts were involved in 24 patients, while in 4 patients only the dorsal pancreatic duct was involved. Marked stricture of the bile duct was detected in 20 patients and their initial symptom was obstructive jaundice. Six patients showed moderate stenosis to 30%-40% of the normal diameter, and the other two patients showed no stenosis of the bile duct. Although marked stricture of the bile duct was detected in 83% (20/24) of patients who showed narrowing of both the ventral and dorsal pancreatic ducts, it was not observed in the 4 patients who showed involvement of the dorsal pancreatic duct alone (P=0.0034).
CONCLUSION
Both the ventral and dorsal pancreatic and bile ducts are involved in patients with autoimmune pancreatitis.
目的
研究自身免疫性胰腺炎患者的胰管和胆管受累情况。
方法
对28例自身免疫性胰腺炎患者的临床及胰胆管造影检查结果进行评估。在本研究中，胰管系统分为三个部分：腹侧胰管；背侧胰管头部；背侧胰管体部和尾部。
结果
24例患者腹侧和背侧胰管均受累，4例患者仅背侧胰管受累。20例患者检测到胆管明显狭窄，其初始症状为梗阻性黄疸。6例患者表现为中度狭窄，为正常管径的30%-40%，另外2例患者胆管无狭窄。虽然在腹侧和背侧胰管均狭窄的患者中83%（20/24）检测到胆管明显狭窄，但在仅背侧胰管受累的4例患者中未观察到（P=0.0034）。
结论
自身免疫性胰腺炎患者腹侧和背侧胰管及胆管均受累。
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