Takakuwa Koichi, Mitsui Takuya, Iwashita Mitsutoshi, Kobayashi Iwao, Suzuki Akira, Oda Takaaki, Torii Yuichi, Matsumoto Masahiko, Yahata Goki, Tanaka Kenichi
Department of Obstetrics and Gynecology, Niigata University School of Medicine, 1-757 Asahimachi-dori, Niigata 951-8510, Japan.
J Perinat Med. 2006;34(1):77-9. doi: 10.1515/JPM.2006.010.
In order to evaluate the prevalence of human papillomavirus (HPV) in the pregnant population in Japan.
We examined cervical swabs of 1,183 pregnant women for HPV DNA using a PCR-RFLP method during October, 2000 and February, 2001. The overall prevalence of HPV in 1,183 pregnant women was analyzed and stratified by age.
The overall prevalence of HPV in pregnant women was 12.5% (148 of 1,183 cases). The prevalence in pregnant women younger than 25 years (22.6%, 28 of 124 cases) was significantly higher compared with that in pregnant women > or =25 years (11.3%, 120 of 1057 cases, P< 0.0005).
The data indicate a significantly higher prevalence of HPV infection in younger pregnant Japanese women.
为了评估日本孕妇人群中人类乳头瘤病毒（HPV）的流行情况。
在2000年10月至2001年2月期间，我们采用聚合酶链反应-限制性片段长度多态性（PCR-RFLP）方法对1183名孕妇的宫颈拭子进行HPV DNA检测。分析了1183名孕妇中HPV的总体流行情况，并按年龄进行分层。
孕妇中HPV的总体流行率为12.5%（1183例中的148例）。年龄小于25岁的孕妇中HPV流行率（22.6%，124例中的28例）显著高于年龄大于或等于25岁的孕妇（11.3%，1057例中的120例，P<0.0005）。
数据表明日本年轻孕妇中HPV感染的流行率显著更高。
