Ni Yike, Montgomery John
Department of Chemistry, Wayne State University, Detroit, Michigan 48202-3489, USA.
J Am Chem Soc. 2006 Mar 1;128(8):2609-14. doi: 10.1021/ja057741q.
A new nickel-catalyzed procedure for the [4+2+1] cycloaddition of (trimethylsilyl)diazomethane with alkynes tethered to dienes has been developed. A broad range of unsaturated substrates participate in the sequence, and stereoselectivities are generally excellent. Stereochemical studies provided evidence for a mechanism that involves the [3,3] sigmatropic rearrangement of divinylcyclopropanes.
已开发出一种新的镍催化方法，用于（三甲基硅基）重氮甲烷与连接到二烯上的炔烃进行[4+2+1]环加成反应。多种不饱和底物参与该反应序列，且立体选择性通常优异。立体化学研究为涉及二乙烯基环丙烷的[3,3] 迁移重排的机理提供了证据。
