Revicki Dennis A, Kimel Miriam, Beusterien Kathy, Kwong Jackie W, Varner Julie A, Ames Michael H, Mahajan Sunny, Cady Roger K
Center for Health Outcomes Research, MEDTAP Institute at UBC, Bethesda, MD 20814, USA.
Headache. 2006 Feb;46(2):240-52. doi: 10.1111/j.1526-4610.2006.00289.x.
To evaluate the psychometric properties of the revised Patient Perception of Migraine Questionnaire (PPMQ-R), which measures satisfaction with migraine treatment.
The original version of the PPMQ was developed prior to the introduction of newer migraine treatments, which may have attributes that influence treatment satisfaction.
Literature review, patient focus groups, and one-on-one patient interviews guided revisions to the original PPMQ. The revised questionnaire was tested in 200 migraine patients visiting neurologists and primary care clinics. At baseline, all subjects completed the PPMQ-R, a migraine-specific quality-of-life measure, and a migraine experience questionnaire; and 125 subjects completed assessments 24 hours after each migraine attack and within 30 days post-baseline. Factor analysis was performed to inform the development of a scoring algorithm, and reliability, validity, and responsiveness of the PPMQ-R were evaluated.
Factor analyses confirmed that the revised questionnaire has five domains measuring satisfaction with efficacy, functionality, ease of use, medication cost, and bothersomeness of medication side effects. A total score can be created by taking the average of efficacy, functionality, and ease of use scores. The PPMQ-R scale scores and Total score demonstrated internal consistency reliability (Cronbach's alpha: 0.80 to 0.98) and test-retest reliability (intra-class correlation coefficient: 0.79 to 0.91). Except for the Cost domain, the PPMQ-R scores discriminated among migraine pain severity levels (all P < .05) and levels of impairment in ability to work and perform usual activities (all P < .05). Except for the Ease of Use and Cost domains, mean PPMQ-R scores were significantly higher among patients with no change in treatment and whose pain improved between two consecutive migraine attacks (all P < .01).
The PPMQ-R is a reliable and valid measure of patient satisfaction with acute migraine treatment in women with frequent migraine attacks.
评估修订后的偏头痛患者感知问卷（PPMQ-R）的心理测量特性，该问卷用于衡量偏头痛治疗的满意度。
PPMQ的原始版本是在更新的偏头痛治疗方法引入之前制定的，而这些新治疗方法可能具有影响治疗满意度的特性。
通过文献综述、患者焦点小组和一对一患者访谈指导对原始PPMQ进行修订。修订后的问卷在200名前往神经科医生和初级保健诊所就诊的偏头痛患者中进行了测试。在基线时，所有受试者完成了PPMQ-R、一项偏头痛特异性生活质量测量以及一份偏头痛体验问卷；125名受试者在每次偏头痛发作后24小时以及基线后30天内完成评估。进行因子分析以指导评分算法的制定，并评估PPMQ-R的信度、效度和反应度。
因子分析证实，修订后的问卷有五个领域，分别衡量对疗效、功能、易用性、药物成本和药物副作用困扰程度的满意度。总分可以通过计算疗效、功能和易用性得分的平均值得出。PPMQ-R量表得分和总分显示出内部一致性信度（克朗巴哈系数：0.80至0.98）和重测信度（组内相关系数：0.79至0.91）。除成本领域外，PPMQ-R得分在偏头痛疼痛严重程度级别（所有P <.05）以及工作和进行日常活动能力的损害程度级别之间存在差异（所有P <.05）。除易用性和成本领域外，在连续两次偏头痛发作之间治疗无变化且疼痛改善的患者中，PPMQ-R平均得分显著更高（所有P <.01）。
PPMQ-R是一种可靠且有效的工具，可用于衡量频繁发作偏头痛的女性对急性偏头痛治疗的患者满意度。
