Ishimaru Y, Nakano S, Nakano H, Oseto M, Yamashita Y
Ishimaru Pediatric Clinic, Matsuyama, Japan.
Acta Paediatr Jpn. 1991 Feb;33(1):50-6. doi: 10.1111/j.1442-200x.1991.tb01519.x.
The epidemiology of rotavirus gastroenteritis was studied in the Matsuyama district from January to May 1988. Among strains of rotaviruses detected 46 showed the group C-specific PAGE pattern of virus RNA. Group C rotavirus gastroenteritis occurred following an epidemic of group A rotavirus infection, primarily in children aged 4-7 years but rarely in those aged 0-1 years. This was seriologically confirmed after the epidemic. Unlike the previous strains detected in Matsuyama in 1985-1986, PAGE of the RNA showed arrangement of the 5th, 6th and 7th segments at similar intervals, suggesting virologic variation. The symptoms of fever, diarrhea and vomiting were milder than in group A rotavirus infection used as a control.
1988年1月至5月，对松山地区轮状病毒肠胃炎的流行病学进行了研究。在检测到的轮状病毒毒株中，有46株呈现出病毒RNA的C组特异性聚丙烯酰胺凝胶电泳（PAGE）图谱。C组轮状病毒肠胃炎在A组轮状病毒感染流行之后发生，主要发生在4至7岁的儿童中，而0至1岁的儿童很少感染。疫情过后通过血清学得到了证实。与1985 - 1986年在松山检测到的先前毒株不同，RNA的PAGE显示第5、6和7个片段以相似的间隔排列，表明存在病毒学变异。发热、腹泻和呕吐症状比作为对照的A组轮状病毒感染要轻。
