Rosa M G, Gattass R, Soares J G
Departamento de Neurobiologia, Universidade Federal do Rio de Janeiro, Cidade Universitária, Brazil.
Exp Brain Res. 1991;84(1):195-209. doi: 10.1007/BF00231775.
We have studied the tangential distribution of cytochrome oxidase (cytox)-rich patches in striate cortex of normal and monocularly enucleated Cebus apella monkeys. Patch spatial density and patch cross-sectional area were analysed in cytox-reacted tangential sections of flat-mounted preparations of V1. In the upper cortical layers of V1, and specially in the middle of layer III, the Cebus has well-delimited cytox-rich patches. Rows of patches are less conspicuous in Cebus than in Old World monkeys. The spatial density of patches is nearly constant throughout the binocular field representation in V1, with a mean value of 4 patches per mm2. In the monocular portions of V1, however, patch spatial density diminishes. In most cases, mean patch cross-sectional area decreases slightly towards the representation of the periphery in V1. However, patches in the representation of the monocular crescent tend to be larger than those in the adjacent binocular representation. The small variation of cytox patch topography with eccentricity contrasts with the large variation of cortical point-image size in V1. In monocularly enucleated monkeys, patches are larger and darker above and below the ocular dominance stripes of the remaining eye than in the alternate stripes. After long-term enucleation, the patches corresponding to the remaining eye columns appeared larger than in normal controls. In contrast, there is no difference in size between the patches located in the deprived and undeprived monocular crescent representations, although both patch and interpatch regions are darker staining in the latter. These results suggest the existence of competitive interactions which modify the cortical intrinsic organization even in adult monkeys.
我们研究了正常和单眼摘除的僧帽猴纹状皮层中富含细胞色素氧化酶（cytox）斑块的切线分布。在V1平展标本的cytox反应切线切片中分析了斑块空间密度和斑块横截面积。在V1的上部皮层，特别是在III层中部，僧帽猴有界限分明的富含cytox的斑块。僧帽猴中斑块的行不如旧世界猴明显。在V1的双眼视野表征中，斑块的空间密度几乎恒定，平均值为每平方毫米4个斑块。然而，在V1的单眼部分，斑块空间密度降低。在大多数情况下，平均斑块横截面积向V1中外周的表征方向略有减小。然而，单眼半月形表征中的斑块往往比相邻双眼表征中的斑块大。cytox斑块地形随偏心率的微小变化与V1中皮质点图像大小的巨大变化形成对比。在单眼摘除的猴子中，在剩余眼睛的眼优势条纹上方和下方的斑块比在交替条纹中的斑块更大、颜色更深。长期摘除后，与剩余眼柱相对应的斑块看起来比正常对照中的更大。相比之下，位于剥夺和未剥夺单眼半月形表征中的斑块大小没有差异，尽管后者的斑块和斑块间区域染色更深。这些结果表明存在竞争性相互作用，即使在成年猴子中也会改变皮质内在组织。
