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1
Should obese women with polycystic ovary syndrome receive treatment for infertility?患有多囊卵巢综合征的肥胖女性应该接受不孕症治疗吗？
BMJ. 2006 Feb 25;332(7539):434-5. doi: 10.1136/bmj.332.7539.434.
2
Obesity, polycystic ovary syndrome, infertility treatment: asking obese women to lose weight before treatment increases stigmatisation.肥胖、多囊卵巢综合征、不孕治疗：要求肥胖女性在治疗前减肥会增加污名化。
BMJ. 2006 Mar 11;332(7541):609. doi: 10.1136/bmj.332.7541.609-b.
3
Obesity, polycystic ovary syndrome, infertility treatment: lifestyle modification is paramount.肥胖、多囊卵巢综合征、不孕治疗：生活方式的改变至关重要。
BMJ. 2006 Mar 11;332(7541):609. doi: 10.1136/bmj.332.7541.609-a.
4
Female obesity and assisted reproductive technologies.女性肥胖与辅助生殖技术。
Semin Reprod Med. 2012 Dec;30(6):507-16. doi: 10.1055/s-0032-1328879. Epub 2012 Oct 16.
5
Obesity and lifestyle management in polycystic ovary syndrome.多囊卵巢综合征中的肥胖与生活方式管理
Clin Obstet Gynecol. 2007 Mar;50(1):277-94. doi: 10.1097/GRF.0b013e31802f54c8.
6
Treatment of infertility in the polycystic ovary syndrome.多囊卵巢综合征的不孕症治疗
N Engl J Med. 2007 May 10;356(19):1999; author reply 2000-1. doi: 10.1056/NEJMc070603.
7
Obesity and infertility.肥胖与不孕。
Curr Opin Endocrinol Diabetes Obes. 2007 Dec;14(6):482-7. doi: 10.1097/MED.0b013e3282f1d6cb.
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Association between polycystic ovary syndrome and glucose intolerance during pregnancy.妊娠期多囊卵巢综合征与葡萄糖耐量异常之间的关联。
J Matern Fetal Med. 1997 Sep-Oct;6(5):303-7. doi: 10.1002/(SICI)1520-6661(199709/10)6:5<303::AID-MFM14>3.0.CO;2-L.
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The influence of obesity on ICSI outcomes in women with polycystic ovary syndrome.肥胖对多囊卵巢综合征女性患者卵胞浆内单精子注射结局的影响。
J Obstet Gynaecol. 2011;31(3):245-9. doi: 10.3109/01443615.2010.546906.
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Basic infertility including polycystic ovary syndrome.基本不孕症，包括多囊卵巢综合征。
Med Clin North Am. 2008 Sep;92(5):1163-92, xi. doi: 10.1016/j.mcna.2008.04.008.

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Interface between reproductive and metabolic dysfunction in polycystic ovary syndrome.多囊卵巢综合征中生殖功能障碍与代谢功能障碍之间的关联
Curr Opin Obstet Gynecol. 2025 Apr 29. doi: 10.1097/GCO.0000000000001037.
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Endocrine Characteristics and Obstetric Outcomes of PCOS Patients with Successful IVF and Non-IVF Pregnancies.多囊卵巢综合征患者体外受精成功与未行体外受精妊娠的内分泌特征及产科结局
J Clin Med. 2024 Sep 21;13(18):5602. doi: 10.3390/jcm13185602.
3
Data-Driven Medicine in the Diagnosis and Treatment of Infertility.数据驱动医学在不孕症诊断与治疗中的应用
J Clin Med. 2022 Oct 29;11(21):6426. doi: 10.3390/jcm11216426.
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The Impact of COVID-19 Lockdown on Weight Loss Program in Infertile Polycystic Ovary Syndrome Women with Obesity.新冠疫情封锁对肥胖型多囊卵巢综合征不孕女性减肥计划的影响。
Obes Facts. 2021;14(6):650-657. doi: 10.1159/000519946. Epub 2021 Nov 1.
5
Adverse effects of female obesity and interaction with race on reproductive potential.女性肥胖的不良影响以及种族因素对生殖潜能的相互作用。
Fertil Steril. 2017 Apr;107(4):868-877. doi: 10.1016/j.fertnstert.2017.02.114.
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A three-component cognitive behavioural lifestyle program for preconceptional weight-loss in women with polycystic ovary syndrome (PCOS): a protocol for a randomized controlled trial.一项针对多囊卵巢综合征（PCOS）女性孕前体重减轻的三成分认知行为生活方式计划：一项随机对照试验方案
Reprod Health. 2017 Mar 6;14(1):34. doi: 10.1186/s12978-017-0295-4.
7
Effects of metformin on pregnancy outcomes in women with polycystic ovary syndrome: A meta-analysis.二甲双胍对多囊卵巢综合征女性妊娠结局的影响：一项荟萃分析。
Medicine (Baltimore). 2016 Sep;95(36):e4526. doi: 10.1097/MD.0000000000004526.
8
Polycystic ovary syndrome in university students: occurrence and associated factors.大学生多囊卵巢综合征：发生率及相关因素
Int J Fertil Steril. 2014 Oct;8(3):261-6. Epub 2014 Nov 1.
9
Metformin use in women with polycystic ovary syndrome.多囊卵巢综合征妇女中二甲双胍的应用。
Ann Transl Med. 2014 Jun;2(6):56. doi: 10.3978/j.issn.2305-5839.2014.04.15.
10
Health related quality of life among different PCOS phenotypes of infertile women.不孕女性不同多囊卵巢综合征表型的健康相关生活质量
J Turk Ger Gynecol Assoc. 2012 Dec 1;13(4):247-52. doi: 10.5152/jtgga.2012.39. eCollection 2012.

本文引用的文献

1
Combined lifestyle modification and metformin in obese patients with polycystic ovary syndrome. A randomized, placebo-controlled, double-blind multicentre study.肥胖多囊卵巢综合征患者联合生活方式干预与二甲双胍治疗：一项随机、安慰剂对照、双盲多中心研究
Hum Reprod. 2006 Jan;21(1):80-9. doi: 10.1093/humrep/dei311. Epub 2005 Sep 30.
2
Effects of obesity on women's reproduction and complications during pregnancy.肥胖对女性生殖及孕期并发症的影响。
Obes Rev. 2004 Aug;5(3):137-43. doi: 10.1111/j.1467-789X.2004.00147.x.
3
Improving reproductive performance in overweight/obese women with effective weight management.通过有效的体重管理提高超重/肥胖女性的生殖能力。
Hum Reprod Update. 2004 May-Jun;10(3):267-80. doi: 10.1093/humupd/dmh018.
4
Maternal morbid obesity and the risk of adverse pregnancy outcome.孕产妇严重肥胖与不良妊娠结局风险
Obstet Gynecol. 2004 Feb;103(2):219-24. doi: 10.1097/01.AOG.0000107291.46159.00.
5
Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome.2003年修订的关于多囊卵巢综合征诊断标准及长期健康风险的共识。
Fertil Steril. 2004 Jan;81(1):19-25. doi: 10.1016/j.fertnstert.2003.10.004.
6
Insulin-sensitising drugs (metformin, troglitazone, rosiglitazone, pioglitazone, D-chiro-inositol) for polycystic ovary syndrome.用于多囊卵巢综合征的胰岛素增敏药物（二甲双胍、曲格列酮、罗格列酮、吡格列酮、D-手性肌醇）
Cochrane Database Syst Rev. 2003(3):CD003053. doi: 10.1002/14651858.CD003053.
7
What is polycystic ovary syndrome? Are national views important?
Hum Reprod. 2002 Sep;17(9):2219-27. doi: 10.1093/humrep/17.9.2219.
8
Impaired glucose tolerance in pregnant women with polycystic ovary syndrome.多囊卵巢综合征孕妇的糖耐量受损。
Obstet Gynecol. 1999 Aug;94(2):194-7. doi: 10.1016/s0029-7844(99)00252-5.
9
Clinical and hormonal characteristics of obese amenorrheic hyperandrogenic women before and after weight loss.肥胖性闭经性高雄激素血症女性体重减轻前后的临床及激素特征
J Clin Endocrinol Metab. 1989 Jan;68(1):173-9. doi: 10.1210/jcem-68-1-173.

Should obese women with polycystic ovary syndrome receive treatment for infertility?

作者信息

Balen Adam H, Dresner Martin, Scott Eleanor M, Drife James O

出版信息

BMJ. 2006 Feb 25;332(7539):434-5. doi: 10.1136/bmj.332.7539.434.

DOI:10.1136/bmj.332.7539.434
PMID:16497735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1382524/
Abstract
摘要