Insel Kathleen, Morrow Daniel, Brewer Barbara, Figueredo Aurelio
University of Arizona, College of Nursing, P.O. 210203, Tucson, AZ, 85721, USA.
J Gerontol B Psychol Sci Soc Sci. 2006 Mar;61(2):P102-7. doi: 10.1093/geronb/61.2.p102.
The purpose of this study was to investigate the association between cognitive processes and medication adherence among community-dwelling older adults. Ninety-five participants (M = 78 years) completed a battery of cognitive assessments including measures of executive function, working memory, cued recall, and recognition memory. Medication adherence was examined over 8 weeks for one prescribed medicine by use of an electronic medication-monitoring cap. In a simultaneous regression, the composite of executive function and working memory tasks was the only significant predictor (beta =.44, p <.01). Findings suggest that assessments of executive function and working memory can be used to identify community-dwelling older adults who may be at risk for failure to take medicines as prescribed.
本研究的目的是调查社区居住的老年人认知过程与药物依从性之间的关联。95名参与者(平均年龄78岁)完成了一系列认知评估,包括执行功能、工作记忆、线索回忆和识别记忆的测量。使用电子药物监测帽对一种处方药的药物依从性进行了为期8周的检查。在同步回归分析中,执行功能和工作记忆任务的综合指标是唯一显著的预测因素(β = 0.44,p < 0.01)。研究结果表明,对执行功能和工作记忆的评估可用于识别可能有未按医嘱服药风险的社区居住老年人。