Belleville Sylvie, Gilbert Brigitte, Fontaine Francine, Gagnon Lise, Ménard Edith, Gauthier Serge
Institut Universitaire de Gériatrie de Montréal, Montreal, Canada.
Dement Geriatr Cogn Disord. 2006;22(5-6):486-99. doi: 10.1159/000096316. Epub 2006 Oct 16.
The efficacy of cognitive training was assessed in persons with mild cognitive impairment (MCI) and persons with normal cognitive aging. Forty-seven participants were included in this study: 28 with MCI and 17 controls. Twenty-one participants received intervention (20 MCI and 9 controls) and 16 participants (8 MCI and 8 controls) received no intervention (waiting-list group). The intervention focused on teaching episodic memory strategies. Three tasks of episodic memory (list recall, face-name association, text memory) were used as primary outcome measures. Results were analyzed using analyses of variance. The intervention effect (pre- and post-intervention difference) was significant on two of the primary outcome measures (delayed list recall and face-name association). A significant pre-post-effect was also found on measures of subjective memory and well-being. There was no improvement in the performance of groups of individuals with MCI and normal elderly persons who did not receive the intervention. These results suggest that persons with MCI can improve their performance on episodic memory when provided with cognitive training.
在轻度认知障碍（MCI）患者和认知功能正常的老年人中评估了认知训练的效果。本研究纳入了47名参与者：28名MCI患者和17名对照者。21名参与者接受了干预（20名MCI患者和9名对照者），16名参与者（8名MCI患者和8名对照者）未接受干预（等待名单组）。干预重点在于教授情景记忆策略。情景记忆的三项任务（列表回忆、面孔-名字联想、文本记忆）被用作主要结局指标。结果采用方差分析进行分析。在两项主要结局指标（延迟列表回忆和面孔-名字联想）上，干预效果（干预前后差异）显著。在主观记忆和幸福感指标上也发现了显著的干预前后效应。未接受干预的MCI患者组和正常老年人组的表现没有改善。这些结果表明，MCI患者在接受认知训练后，情景记忆表现可以得到改善。
