Rocca Rodolfo, De Angelis Claudio, Castellino Francesca, Masoero Guya, Daperno Marco, Sostegni Raffaello, Rigazio Caterina, Crocellà Lucia, Lavagna Alessandro, Ercole Elena, Pera Angelo
Gastroenterology Department, ASO Ordine Mauriziano Hospital, Torino, Italy.
Gastrointest Endosc. 2006 Mar;63(3):479-84. doi: 10.1016/j.gie.2005.11.042.
MRCP and EUS have replaced ERCP in the diagnosis of biliary diseases, but the latter is needed for treatment. This study evaluates a new approach in the management of common bile duct stones, by using an oblique-viewing echoendoscope.
Nineteen patients with acute abdominal pain associated with increased liver tests entered the study. Evaluation of the biliary tree was performed by using an oblique-viewing echoendoscope (JF-UM20; Olympus Europe GmbH, Hamburg, Germany). When biliary stones or sludge were found, bile duct cannulation and sphincterotomy were performed in the same session.
Bile duct stones were diagnosed by EUS in 4 patients and biliary sludge in 12; the subsequent cholangiography and sphincterotomy with stone extraction confirmed the diagnosis in all patients. Bile duct cannulation failed in 1 patient. EUS showed features of chronic pancreatitis in 3 cases. The mean time for the whole procedure (EUS plus endoscopic retrograde cholangiography with biliary treatment) was 27 minutes. No procedure-related complications were observed.
This new approach appears to be feasible and safe, providing an accurate diagnosis and, at the same time, an appropriate treatment of common bile duct stones when needed. With technical improvements, this extended EUS technique could be used as the first-line procedure in patients with biliopancreatic diseases.
磁共振胰胆管造影(MRCP)和超声内镜(EUS)已在胆管疾病诊断中取代了内镜逆行胰胆管造影(ERCP),但后者仍用于治疗。本研究评估了一种使用斜视超声内镜管理胆总管结石的新方法。
19例伴有肝功能检查指标升高的急性腹痛患者进入本研究。使用斜视超声内镜(JF-UM20;德国汉堡奥林巴斯欧洲有限公司)对胆管树进行评估。当发现胆管结石或胆泥时,在同一次操作中进行胆管插管和括约肌切开术。
EUS诊断出4例胆管结石和12例胆泥;随后的胆管造影和括约肌切开取石术证实了所有患者的诊断。1例患者胆管插管失败。EUS显示3例有慢性胰腺炎特征。整个操作(EUS加内镜逆行胆管造影及胆管治疗)的平均时间为27分钟。未观察到与操作相关的并发症。
这种新方法似乎可行且安全,能提供准确诊断,同时在需要时对胆总管结石进行适当治疗。随着技术改进,这种扩展的EUS技术可用于胆胰疾病患者的一线治疗。