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无皮肤受累的致命性水痘-带状疱疹病毒脑脊神经根炎

Fatal varicella-zoster virus meningoradiculitis without skin involvement.

作者信息

Dueland A N, Devlin M, Martin J R, Mahalingam R, Cohrs R, Manz H, Trombley I, Gilden D

机构信息

Department of Neurology, University of Colorado School of Medicine, Denver 80262.

出版信息

Ann Neurol. 1991 May;29(5):569-72. doi: 10.1002/ana.410290520.

Abstract

A 77-year-old man with T-cell lymphoma developed an acute fatal meningoradiculitis of cranial nerve roots and cauda equina, pathologically and virologically confirmed to be caused by varicella-zoster virus. This is the first report of fatal varicella-zoster virus-induced neurological disease in the absence of skin lesions. Varicella-zoster virus should be included in the differential diagnosis of acute radiculoneuropathy in the immunocompromised patient, particularly because antiviral treatment for varicella-zoster virus exists.

摘要

一名77岁的T细胞淋巴瘤男性患者发生了一种急性致命性的颅神经根和马尾神经脊膜炎,经病理和病毒学证实由水痘-带状疱疹病毒引起。这是首例在无皮肤损害情况下由水痘-带状疱疹病毒引起的致命性神经系统疾病的报告。在免疫功能低下患者的急性神经根神经病鉴别诊断中应考虑水痘-带状疱疹病毒,特别是因为存在针对水痘-带状疱疹病毒的抗病毒治疗。

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