类固醇滥用后播散性水痘带状疱疹病毒感染及无症状性水痘带状疱疹病毒血管病
Disseminated VZV infection and asymptomatic VZV vasculopathy after steroid abuse.
作者信息
Nagel Maria A, Lenggenhager Daniela, White Teresa, Khmeleva Nelly, Heintzman Anna, Boyer Philip J, Gilden Don
机构信息
Department of Neurology, University of Colorado School of Medicine, Aurora, CO, United States.
Institute of Pathology, Kantonsspital, St. Gallen, Switzerland.
出版信息
J Clin Virol. 2015 May;66:72-5. doi: 10.1016/j.jcv.2015.03.016. Epub 2015 Mar 18.
Abstract
A 60-year-old man who abused corticosteroids developed thoracic-distribution zoster. Varicella zoster virus (VZV) DNA was found in non-healing skin 3 months later. He died suddenly 2 months later. Skin was ulcerated and necrotic. VZV was widespread in organs and arteries, particularly coronary arteries and aorta, with VZV vasculopathy in the posterior cerebral artery.
摘要
一名长期滥用皮质类固醇的60岁男性患上了胸段带状疱疹。3个月后，在未愈合的皮肤中发现了水痘带状疱疹病毒（VZV）DNA。2个月后，他突然死亡。皮肤出现溃疡和坏死。VZV在器官和动脉中广泛存在，尤其是冠状动脉和主动脉，大脑后动脉出现了VZV血管病变。
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