Dubner Steve, Bovi Joseph, White Julia, Susnik Barbara
Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.
Breast J. 2006 Mar-Apr;12(2):173-6. doi: 10.1111/j.1075-122X.2006.00229.x.
We present the case of a 52-year-old woman who underwent lumpectomy and radiation therapy for breast carcinoma and 2 years later presented with changes limited to the breast radiation field including hyperpigmentation, retraction, and skin thickening. These clinical features, along with pathologic findings, were diagnostic of postirradiation morphea. It is important to be aware of this rare complication of radiation therapy because it clinically presents with symptoms mimicking malignancy and may be misinterpreted as recurrent carcinoma or even angiosarcoma.
我们报告了一例52岁女性病例，该患者因乳腺癌接受了乳房肿瘤切除术和放射治疗，2年后出现仅限于乳房放射野的变化，包括色素沉着、皮肤回缩和皮肤增厚。这些临床特征以及病理结果诊断为放射后硬斑病。认识到放射治疗的这种罕见并发症很重要，因为其临床症状类似恶性肿瘤，可能会被误诊为复发性癌甚至血管肉瘤。
