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辐射诱导硬斑病:X 射线作为自身免疫的触发因素。

Irradiation-induced morphea: x-rays as triggers of autoimmunity.

机构信息

Department of Dermatology, Triemli Hospital, Zurich, Switzerland.

出版信息

Dermatology. 2011;223(1):9-12. doi: 10.1159/000330324. Epub 2011 Aug 25.

DOI:10.1159/000330324
PMID:21865672
Abstract

We report on 3 females with breast cancer who developed morphea at the site of post-surgery radiotherapy. One was suffering from other autoimmune skin diseases before the diagnosis and treatment of breast cancer. Postirradiation morphea is a potential complication after radiotherapy, particularly radiotherapy for cancer. This troublesome skin disease can occur months to years after treatment, and is associated with remarkable morbidity and pain, and also cosmetic aspects. Therefore, it is crucial to be aware of this condition, and to try to identify patients who might be at an increased risk of developing morphea.

摘要

我们报告了 3 例女性乳腺癌患者,她们在术后放疗部位发生了硬斑病。其中 1 例在诊断和治疗乳腺癌之前患有其他自身免疫性皮肤病。放疗后硬斑病是放疗后尤其是癌症放疗的一种潜在并发症。这种麻烦的皮肤病可在治疗后数月至数年内发生,并伴有显著的发病率和疼痛,以及美容方面的问题。因此,了解这种情况并试图确定可能有更高风险发生硬斑病的患者至关重要。

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