Shibli S M A, Beenakumari K S, Suma N D
Department of Chemistry, University of Kerala, Kariavottom Campus, Trivandrum, Kerala 695581, India.
Biosens Bioelectron. 2006 Dec 15;22(5):633-8. doi: 10.1016/j.bios.2006.01.020. Epub 2006 Mar 9.
Pure nickel electrodes can be used as biosensors especially for sensing and estimating acetylcholine neurotransmitter. In the present work, a good electrochemical sensor was developed by electroplating nano nickel oxide reinforced nickel on graphite substrate. The morphology of the working electrode surface was studied by using a scanning electron microscope (SEM). The electrochemical and biological performance of the modified electrode was characterized by polarization studies in different media. The present modified electrode showed good sensing performance with a response time as low as 8s during sensing and estimation of acetylcholine. The sensitivity of the modified electrode was 34.88 microA/(microM cm(2)).
纯镍电极可用作生物传感器，尤其用于传感和估算乙酰胆碱神经递质。在本工作中，通过在石墨基底上电沉积纳米氧化镍增强镍，开发出了一种良好的电化学传感器。使用扫描电子显微镜（SEM）研究了工作电极表面的形态。通过在不同介质中的极化研究对修饰电极的电化学和生物学性能进行了表征。在乙酰胆碱的传感和估算过程中，当前的修饰电极显示出良好的传感性能，响应时间低至8秒。修饰电极的灵敏度为34.88微安/（微摩尔·平方厘米）。
