Trendafilova Antoaneta, Todorova Milka, Mikhova Bozhanka, Vitkova Antonina, Duddeck Helmut
Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences, Sofia.
Phytochemistry. 2006 Apr;67(8):764-70. doi: 10.1016/j.phytochem.2006.01.033. Epub 2006 Mar 13.
The flower heads of Achillea collina afforded 31 individual sesquiterpene lactones, among which nine guaianolides (1, 16, 20, 21, 23, 27-30), a germacranolide (18) and a dimeric guaianolide (31) were found to be new natural products. The lactones 2-4, 12, 14, 15, 17, 19 and 25 were isolated for the first time from the investigated species. Their structures were established by spectral methods.
牛至（Achillea collina）的头状花序含有31种倍半萜内酯，其中9种愈创木烷型内酯（1、16、20、21、23、27 - 30）、1种吉马烷型内酯（18）和1种二聚体愈创木烷型内酯（31）被发现是新的天然产物。内酯2 - 4、12、14、15、17、19和25首次从该研究物种中分离得到。它们的结构通过光谱方法确定。
