García-Monlleó Rosa M, Rivas Maria J, Huertas Rafael, Melgosa Manuel
Departamento de Optica, Facultad de Ciencia, Universidad de Granada, Granada, Spain.
Optom Vis Sci. 2006 Mar;83(3):160-5. doi: 10.1097/01.opx.0000204521.62853.3a.
The color change reached in two commercial disinfecting solutions for soft contact lenses using new color indicators has been analyzed, and its relationship with the temporal evolution of the hydrogen peroxide concentration, responsible for the disinfection process, has been examined. The results are compared with another commercial solution using a different color indicator.
Color measurements of the disinfecting solutions were performed at 2-minute intervals for over 2 hours using a Photo-Research PR-704 spectroradiometer with horizontal optical axis. Samples were placed at the floor of a VeriVide CAC 120 light booth with a Munsell gray mask behind them. Two different standard light sources, representative of outdoor and indoor illumination, were used. The hydrogen peroxide concentration during the disinfection process was measured for each commercial solution using a Beckman DU-7 spectrophotometer.
The temporal evolutions of color for the two new disinfecting solutions were qualitatively different. CIELAB color differences induced in these two new disinfecting solutions were 1.5 and 2.2 times greater than that measured in the earlier comparative solution and occur in a more appropriate direction of color space for users with defective color vision. Although the earlier solution generated color changes close to the deutan confusion line, the changes produced by the new solutions are close to the tritan confusion line. After 2 hours, the hydrogen peroxide concentration for the two new solutions was approximately one-third the one reached by the earlier solution. There are statistically significant correlations (p < 0.01) between color change and hydrogen peroxide concentration for the two new solutions (r = -0.878 and r = -0.990).
Color changes in these hydrogen peroxide systems can be used as a safe and useful tool by contact lens wearers. The two new disinfecting solutions analyzed in this article show noteworthy improvements over the earlier solution.
分析了两种使用新型颜色指示剂的市售软性隐形眼镜消毒溶液所达到的颜色变化，并研究了其与负责消毒过程的过氧化氢浓度随时间变化的关系。将结果与另一种使用不同颜色指示剂的市售溶液进行了比较。
使用水平光轴的Photo-Research PR-704分光辐射计，每隔2分钟对消毒溶液进行一次颜色测量，持续2小时以上。样品放置在VeriVide CAC 120灯箱底部，后面有一个孟塞尔灰色遮罩。使用了两种不同的代表室外和室内照明的标准光源。使用贝克曼DU-7分光光度计测量每种市售溶液在消毒过程中的过氧化氢浓度。
两种新型消毒溶液的颜色随时间的变化在性质上有所不同。这两种新型消毒溶液引起的CIELAB颜色差异比早期比较溶液中测得的颜色差异分别大1.5倍和2.2倍，并且对于色觉有缺陷的用户而言，其发生在更合适的颜色空间方向上。尽管早期溶液产生的颜色变化接近绿色盲混淆线，但新型溶液产生的变化接近蓝色盲混淆线。2小时后，两种新型溶液的过氧化氢浓度约为早期溶液所达到浓度的三分之一。两种新型溶液的颜色变化与过氧化氢浓度之间存在统计学上的显著相关性（p < 0.01）（r = -0.878和r = -0.990）。
这些过氧化氢系统中的颜色变化可被隐形眼镜佩戴者用作安全且有用的工具。本文分析的两种新型消毒溶液相对于早期溶液显示出显著的改进。
