南五味子茎中的四种新木脂素。

Four new lignans from the stems of Kadsura heteroclita.

作者信息

Wang Wei, Liu Jinzhi, Liu Rongxia, Xu Zhengren, Yang Min, Wang Weixing, Liu Peng, Sabia Gular, Wang Xiaoming, Guo Dean

机构信息

The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, PR China.

出版信息

Planta Med. 2006 Feb;72(3):284-8. doi: 10.1055/s-2005-916213.

DOI:10.1055/s-2005-916213

PMID:16534740

Abstract

Two new C(18) dibenzocyclooctadiene lignans named heteroclitalignans A and B (1 and 3), one new C(19) homolignan named heteroclitalignan C(4) and one new natural product named heteroclitalignan D(2), together with the four known lignans kadsurarin (5), kadsulignan E (6), d-epigalbacin, and meso-dihydroguaiaretic acid were isolated from the stems of Kadsura heteroclita. The structures of these compounds were characterized by extensive 1D and 2D NMR spectral data analysis.

摘要

从异型南五味子茎中分离得到两个新的C(18)二苯并环辛二烯木脂素，命名为异型南五味子木脂素A和B（1和3），一个新的C(19)高木脂素，命名为异型南五味子木脂素C（4），以及一个新的天然产物，命名为异型南五味子木脂素D（2），同时还得到了四个已知木脂素，南五味子素（5）、南五味子木脂素E（6）、d-表加巴辛和内消旋二氢愈创木酸。通过广泛的一维和二维核磁共振光谱数据分析对这些化合物的结构进行了表征。