Nitric oxide and cisplatin resistance: NO easy answers.
作者信息
Turchi John J
机构信息
Department of Medicine and Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, 1044 West Walnut Street, R4-202, Indianapolis, IN 46202, USA.
出版信息
Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4337-8. doi: 10.1073/pnas.0601001103. Epub 2006 Mar 13.
Abstract
摘要
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本文引用的文献
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Reversal to cisplatin sensitivity in recurrent human ovarian cancer cells by NCX-4016, a nitro derivative of aspirin.阿司匹林的硝基衍生物NCX-4016使复发性人卵巢癌细胞对顺铂重新敏感
Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3914-9. doi: 10.1073/pnas.0511250103. Epub 2006 Feb 23.
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Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets.谷胱甘肽S-转移酶作为激酶途径的调节因子和抗癌药物靶点。
Methods Enzymol. 2005;401:287-307. doi: 10.1016/S0076-6879(05)01019-0.
3
Nitric oxide-donating aspirin induces apoptosis in human colon cancer cells through induction of oxidative stress.释放一氧化氮的阿司匹林通过诱导氧化应激来诱导人结肠癌细胞凋亡。
Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17207-12. doi: 10.1073/pnas.0506893102. Epub 2005 Nov 10.
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Nitric oxide-donating aspirin inhibits colon cancer cell growth via mitogen-activated protein kinase activation.一氧化氮供体型阿司匹林通过丝裂原活化蛋白激酶激活抑制结肠癌细胞生长。
J Pharmacol Exp Ther. 2006 Jan;316(1):25-34. doi: 10.1124/jpet.105.091363. Epub 2005 Sep 16.
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Platinums: extending their therapeutic spectrum.铂类药物：拓展其治疗谱
J Chemother. 2004 Nov;16 Suppl 4:77-82. doi: 10.1179/joc.2004.16.Supplement-1.77.
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Positional isomerism markedly affects the growth inhibition of colon cancer cells by nitric oxide-donating aspirin in vitro and in vivo.位置异构显著影响体外和体内释放一氧化氮的阿司匹林对结肠癌细胞的生长抑制作用。
J Pharmacol Exp Ther. 2005 Mar;312(3):978-88. doi: 10.1124/jpet.104.075994. Epub 2004 Nov 4.
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In vitro metabolism of nitric oxide-donating aspirin: the effect of positional isomerism.一氧化氮供体型阿司匹林的体外代谢：位置异构的影响。
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NO-donating nonsteroidal antiinflammatory drugs (NSAIDs) inhibit colon cancer cell growth more potently than traditional NSAIDs: a general pharmacological property?一氧化氮供体型非甾体抗炎药（NSAIDs）比传统NSAIDs更有效地抑制结肠癌细胞生长：一种普遍的药理学特性？
Biochem Pharmacol. 2004 Jun 15;67(12):2197-205. doi: 10.1016/j.bcp.2004.02.027.
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Nitric oxide inhibits DNA-adduct excision in nucleotide excision repair.一氧化氮抑制核苷酸切除修复中的DNA加合物切除。
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