Jacobi C, Stingele K, Kretz R, Hartmann M, Storch-Hagenlocher B, Breitbart A, Wildemann B
Department of Neurology, University of Heidelberg, Heidelberg, Germany.
Lupus. 2006;15(2):107-9. doi: 10.1191/0961203306lu2265cr.
Neurologic symptoms rarely occur as presenting feature of systemic lupus erythematosus (SLE). We describe a 37-year old woman who presented with several episodes of transverse myelitis and optic neuritis. Clinical, radiologic and laboratory findings were compatible with neuromyelitis optica (NMO). Seven years after disease onset clinical and laboratory findings were diagnostic for SLE. This case illustrates that NMO may represent a first manifestation of SLE for many years.
神经系统症状很少作为系统性红斑狼疮(SLE)的首发特征出现。我们描述了一名37岁女性,她出现了几次横贯性脊髓炎和视神经炎发作。临床、影像学和实验室检查结果与视神经脊髓炎(NMO)相符。发病7年后,临床和实验室检查结果确诊为SLE。该病例表明,NMO可能多年来一直是SLE的首发表现。