感染后嗅觉丧失患者的嗅觉功能和嗅球体积
Olfactory function and olfactory bulb volume in patients with postinfectious olfactory loss.
作者信息
Rombaux Philippe, Mouraux André, Bertrand Bernard, Nicolas Georges, Duprez Thierry, Hummel Thomas
机构信息
Department of Otorhinolaryngology, Cliniques Universitaires Saint Luc, Brussels, Belgium.
出版信息
Laryngoscope. 2006 Mar;116(3):436-9. doi: 10.1097/01.MLG.0000195291.36641.1E.
OBJECTIVE
The study aimed to investigate whether the degree of postinfectious olfactory loss is reflected in volume of the olfactory bulb (OB).
STUDY DESIGN
Retrospective study of 26 patients with postinfectious olfactory loss.
MATERIALS AND METHODS
Olfactory function was assessed with the "Sniffin' Sticks" test kit, and the magnetic resonance imaging study focused on OB volume and the olfactory sulcus.
RESULTS
The study revealed that 1) OB volume varies with regard to olfactory function, 2) OB volume decreases with duration of olfactory loss, and 3) patients with parosmia had smaller OB volumes than patients who did not report such smell distortions, although their overall olfactory function was not significantly different from each other.
CONCLUSION
The study emphasizes that OB volume is a gauge of olfactory function.
目的
本研究旨在调查感染后嗅觉丧失的程度是否可通过嗅球（OB）的体积反映出来。
研究设计
对26例感染后嗅觉丧失患者进行回顾性研究。
材料与方法
使用“嗅棒”测试套件评估嗅觉功能，磁共振成像研究聚焦于嗅球体积和嗅沟。
结果
研究表明，1）嗅球体积随嗅觉功能而变化，2）嗅球体积随嗅觉丧失持续时间而减小，3）嗅觉倒错患者的嗅球体积比未报告此类嗅觉扭曲的患者小，尽管他们的总体嗅觉功能彼此无显著差异。
结论
该研究强调嗅球体积是嗅觉功能的一个指标。
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