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微波频率范围内动物肝脏组织的超宽带温度相关介电特性

Ultrawideband temperature-dependent dielectric properties of animal liver tissue in the microwave frequency range.

作者信息

Lazebnik Mariya, Converse Mark C, Booske John H, Hagness Susan C

机构信息

Department of Electrical and Computer Engineering, University of Wisconsin, Madison, WI 53705, USA.

出版信息

Phys Med Biol. 2006 Apr 7;51(7):1941-55. doi: 10.1088/0031-9155/51/7/022. Epub 2006 Mar 21.

Abstract

The development of ultrawideband (UWB) microwave diagnostic and therapeutic technologies, such as UWB microwave breast cancer detection and hyperthermia treatment, is facilitated by accurate knowledge of the temperature- and frequency-dependent dielectric properties of biological tissues. To this end, we characterize the temperature-dependent dielectric properties of a representative tissue type-animal liver-from 0.5 to 20 GHz. Since discrete-frequency linear temperature coefficients are impractical and inappropriate for applications spanning wide frequency and temperature ranges, we propose a novel and compact data representation technique. A single-pole Cole-Cole model is used to fit the dielectric properties data as a function of frequency, and a second-order polynomial is used to fit the Cole-Cole parameters as a function of temperature. This approach permits rapid estimation of tissue dielectric properties at any temperature and frequency.

摘要

超宽带(UWB)微波诊断和治疗技术的发展,如UWB微波乳腺癌检测和热疗,需要准确了解生物组织随温度和频率变化的介电特性。为此,我们对一种代表性组织类型——动物肝脏——在0.5至20 GHz频率范围内随温度变化的介电特性进行了表征。由于离散频率线性温度系数对于跨越宽频率和温度范围的应用不切实际且不合适,我们提出了一种新颖且紧凑的数据表示技术。使用单极Cole-Cole模型来拟合作为频率函数的介电特性数据,并使用二阶多项式来拟合作为温度函数的Cole-Cole参数。这种方法允许在任何温度和频率下快速估计组织介电特性。

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