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青光眼筛查:当前趋势、经济问题、技术与挑战。

Glaucoma screening: current trends, economic issues, technology, and challenges.

作者信息

Nduaguba Constance, Lee Richard K

机构信息

Scheie Eye Institute, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.

出版信息

Curr Opin Ophthalmol. 2006 Apr;17(2):142-52. doi: 10.1097/01.icu.0000193088.75432.c9.

Abstract

PURPOSE OF REVIEW

Glaucoma is one of the leading causes of irreversible blindness worldwide. Early glaucoma detection and treatment are currently the only known methods for preventing blindness and low vision resulting from this frequently asymptomatic disease.

RECENT FINDINGS

New technologies for detecting early glaucomatous damage are important in diagnosing optic nerve disease, not only in community screening settings but also in clinics. Imaging of the optic nerve head and macula and retinal nerve fiber layer analysis can provide quick, automated, and quantitative measurements in agreement with clinical estimates of optic disc structure and visual function. In the area of perimetry, frequency-doubling technology is a promising and feasible mass-screening method with reasonable sensitivity for detecting visual field loss. Central corneal thickness has emerged as a new risk factor for the development and progression of glaucoma, thereby complicating the role of tonometry and measurement of intraocular pressure as screening parameters for glaucoma. Along with technological advances, strides are also being made with public policy and legislative efforts to bring glaucoma onto the national and global health care agenda. These initiatives incorporate vision-screening goals into national disease prevention programs emphasizing the need for early glaucoma detection and treatment.

SUMMARY

Glaucoma awareness needs to be increased through better education, and compliance with follow-up care needs to be improved to decrease the economic and social costs from glaucoma. In addition, screening models need to be developed that will be effective in developing countries where the risk of blindness from glaucoma is highest.

摘要

综述目的

青光眼是全球不可逆性失明的主要原因之一。早期青光眼检测和治疗是目前预防这种通常无症状疾病导致失明和视力低下的唯一已知方法。

最新发现

检测早期青光眼损害的新技术对于诊断视神经疾病很重要,不仅在社区筛查环境中,在诊所中也是如此。视神经乳头和黄斑成像以及视网膜神经纤维层分析可以提供与视盘结构和视觉功能的临床评估相一致的快速、自动化和定量测量。在视野检查领域,倍频技术是一种有前景且可行的大规模筛查方法,对检测视野缺损具有合理的敏感性。中央角膜厚度已成为青光眼发生和进展的一个新危险因素,从而使眼压测量和眼压作为青光眼筛查参数的作用变得复杂。随着技术进步,在公共政策和立法努力方面也取得了进展,将青光眼纳入国家和全球医疗保健议程。这些举措将视力筛查目标纳入国家疾病预防计划,强调早期青光眼检测和治疗的必要性。

总结

需要通过更好的教育提高对青光眼的认识,并改善对后续治疗的依从性,以降低青光眼造成的经济和社会成本。此外,需要开发在青光眼致盲风险最高的发展中国家有效的筛查模式。

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